Apparent inadequacy of L-dopa stimulation as a clinical test of growth hormone release

C. Gómez-Sánchez, Norman M Kaplan

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

The use of a single, oral, 500-mg dose of L-dopa has been compared to the arginineinsulin test as a stimulus for growth hormone (hGH) release in 15 patients. Whereas L-dopa induced a significant rise in hGH in 5 of 6 normals, it failed to do so in all 3 obese subjects, one patient with short stature and one with an enlarged sella, all of whom responded to arginineinsulin. The response to L-dopa in 2 hypothyroid patients was blunted. The hGH response to L-dopa appears to have limited usefulness in the clinical assessment of pituitary function.

Original languageEnglish (US)
Pages (from-to)1105-1107
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume34
Issue number6
DOIs
StatePublished - Jan 1 1972

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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