The use of a single, oral, 500-mg dose of L-dopa has been compared to the arginineinsulin test as a stimulus for growth hormone (hGH) release in 15 patients. Whereas L-dopa induced a significant rise in hGH in 5 of 6 normals, it failed to do so in all 3 obese subjects, one patient with short stature and one with an enlarged sella, all of whom responded to arginineinsulin. The response to L-dopa in 2 hypothyroid patients was blunted. The hGH response to L-dopa appears to have limited usefulness in the clinical assessment of pituitary function.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Clinical Biochemistry
- Biochemistry, medical