Applications of magnetic nanoparticles in biomedicine

Carlos Bárcena, Amandeep K. Sra, Jinming Gao

Research output: Chapter in Book/Report/Conference proceedingChapter

26 Scopus citations

Abstract

In recent years, magnetic nanoparticles have played an increasing role in biomedical applications and have been the subject of extensive research investigations. Physical properties, including nanoparticle size, composition, and surface chemistry, vary widely and influence their biological and pharmacological properties and, ultimately, their clinical applications. Among different magnetic nanoparticles, superparamagnetic iron oxide nanoparticles (SPIOs) were found nontoxic and used as magnetic resonance imaging (MRI) contrast agents, in molecular and cellular imaging applications. SPIOs are used in detection of liver metastases, metastatic lymph nodes, and inflammatory and/or neural degenerative diseases. In addition, drug delivery via magnetic targeting, hyperthermia, and labeling/∈tracking of stem cells have also been explored as potential therapeutic options.

Original languageEnglish (US)
Title of host publicationNanoscale Magnetic Materials and Applications
PublisherSpringer US
Pages591-626
Number of pages36
ISBN (Print)9780387855981
DOIs
StatePublished - Dec 1 2009

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ASJC Scopus subject areas

  • Engineering(all)

Cite this

Bárcena, C., Sra, A. K., & Gao, J. (2009). Applications of magnetic nanoparticles in biomedicine. In Nanoscale Magnetic Materials and Applications (pp. 591-626). Springer US. https://doi.org/10.1007/978-0-387-85600-1_20