Abstract
Purpose of review: This review focuses on recent developments in three controversial areas of management of acute coronary syndromes. Recent findings: There are potential benefits of an early invasive treatment strategy (routine cardiac catheterization and revascularization when appropriate) in the elderly, who are at high risk for adverse outcomes and treatment-related complications following acute coronary syndromes. There are developments in the role of low-molecular-weight heparin agents in management of acute coronary syndromes in the modern treatment era, in which early coronary revascularization and use of other potent antiplatelet and antithrombin agents are common. Finally, this review looks at emerging data and controversy regarding the effects of intensive lipid-lowering treatment early after acute coronary syndrome. Recent clinical trials have yielded contradictory results. Summary: This paper evaluates recent evidence in acute coronary syndromes regarding early invasive revascularization strategies in high risk elderly patients, and also discusses controversies regarding the role of low molecular weight heparin and intensive statin regimens.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 536-540 |
| Number of pages | 5 |
| Journal | Current Opinion in Cardiology |
| Volume | 20 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 2005 |
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Keywords
- Acute coronary syndromes
- Age
- Anticoagulation
- Lipid
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Appropriate invasive and conservative strategies for patients with non-ST elevation acute coronary syndromes. / Mehta, Sameer K.; de Lemos, James A.
In: Current Opinion in Cardiology, Vol. 20, No. 6, 11.2005, p. 536-540.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Appropriate invasive and conservative strategies for patients with non-ST elevation acute coronary syndromes
AU - Mehta, Sameer K.
AU - de Lemos, James A
PY - 2005/11
Y1 - 2005/11
N2 - Purpose of review: This review focuses on recent developments in three controversial areas of management of acute coronary syndromes. Recent findings: There are potential benefits of an early invasive treatment strategy (routine cardiac catheterization and revascularization when appropriate) in the elderly, who are at high risk for adverse outcomes and treatment-related complications following acute coronary syndromes. There are developments in the role of low-molecular-weight heparin agents in management of acute coronary syndromes in the modern treatment era, in which early coronary revascularization and use of other potent antiplatelet and antithrombin agents are common. Finally, this review looks at emerging data and controversy regarding the effects of intensive lipid-lowering treatment early after acute coronary syndrome. Recent clinical trials have yielded contradictory results. Summary: This paper evaluates recent evidence in acute coronary syndromes regarding early invasive revascularization strategies in high risk elderly patients, and also discusses controversies regarding the role of low molecular weight heparin and intensive statin regimens.
AB - Purpose of review: This review focuses on recent developments in three controversial areas of management of acute coronary syndromes. Recent findings: There are potential benefits of an early invasive treatment strategy (routine cardiac catheterization and revascularization when appropriate) in the elderly, who are at high risk for adverse outcomes and treatment-related complications following acute coronary syndromes. There are developments in the role of low-molecular-weight heparin agents in management of acute coronary syndromes in the modern treatment era, in which early coronary revascularization and use of other potent antiplatelet and antithrombin agents are common. Finally, this review looks at emerging data and controversy regarding the effects of intensive lipid-lowering treatment early after acute coronary syndrome. Recent clinical trials have yielded contradictory results. Summary: This paper evaluates recent evidence in acute coronary syndromes regarding early invasive revascularization strategies in high risk elderly patients, and also discusses controversies regarding the role of low molecular weight heparin and intensive statin regimens.
KW - Acute coronary syndromes
KW - Age
KW - Anticoagulation
KW - Lipid
UR - http://www.scopus.com/inward/record.url?scp=27644455500&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=27644455500&partnerID=8YFLogxK
U2 - 10.1097/01.hco.0000179820.72953.65
DO - 10.1097/01.hco.0000179820.72953.65
M3 - Article
C2 - 16234627
AN - SCOPUS:27644455500
VL - 20
SP - 536
EP - 540
JO - Current Opinion in Cardiology
JF - Current Opinion in Cardiology
SN - 0268-4705
IS - 6
ER -