Abstract
Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2692-2700 |
| Number of pages | 9 |
| Journal | European Heart Journal |
| Volume | 37 |
| Issue number | 35 |
| DOIs | |
| State | Published - Sep 14 2016 |
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Keywords
- Cardiovascular outcome
- Chronic total occlusion
- Guidelines
- PCI
- Quality of life
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Appropriateness of percutaneous revascularization of coronary chronic total occlusions : An overview. / Galassi, Alfredo R.; Brilakis, Emmanouil S.; Boukhris, Marouane; Tomasello, Salvatore D.; Sianos, Georgios; Karmpaliotis, Dimitri; Di Mario, Carlo; Strauss, Bradley H.; Rinfret, Stephane; Yamane, Masahisa; Katoh, Osamu; Werner, Gerald S.; Reifart, Nicolaus.
In: European Heart Journal, Vol. 37, No. 35, 14.09.2016, p. 2692-2700.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Appropriateness of percutaneous revascularization of coronary chronic total occlusions
T2 - An overview
AU - Galassi, Alfredo R.
AU - Brilakis, Emmanouil S.
AU - Boukhris, Marouane
AU - Tomasello, Salvatore D.
AU - Sianos, Georgios
AU - Karmpaliotis, Dimitri
AU - Di Mario, Carlo
AU - Strauss, Bradley H.
AU - Rinfret, Stephane
AU - Yamane, Masahisa
AU - Katoh, Osamu
AU - Werner, Gerald S.
AU - Reifart, Nicolaus
PY - 2016/9/14
Y1 - 2016/9/14
N2 - Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.
AB - Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.
KW - Cardiovascular outcome
KW - Chronic total occlusion
KW - Guidelines
KW - PCI
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84990890015&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84990890015&partnerID=8YFLogxK
U2 - 10.1093/eurheartj/ehv391
DO - 10.1093/eurheartj/ehv391
M3 - Review article
C2 - 26254179
AN - SCOPUS:84990890015
VL - 37
SP - 2692
EP - 2700
JO - European Heart Journal
JF - European Heart Journal
SN - 0195-668X
IS - 35
ER -