Appropriateness of percutaneous revascularization of coronary chronic total occlusions: An overview

Alfredo R. Galassi; Emmanouil S. Brilakis; Marouane Boukhris; Salvatore D. Tomasello; Georgios Sianos; Dimitri Karmpaliotis; Carlo Di Mario; Bradley H. Strauss; Stephane Rinfret; Masahisa Yamane; Osamu Katoh; Gerald S. Werner; Nicolaus Reifart

doi:10.1093/eurheartj/ehv391

Appropriateness of percutaneous revascularization of coronary chronic total occlusions: An overview

Alfredo R. Galassi, Emmanouil S. Brilakis, Marouane Boukhris, Salvatore D. Tomasello, Georgios Sianos, Dimitri Karmpaliotis, Carlo Di Mario, Bradley H. Strauss, Stephane Rinfret, Masahisa Yamane, Osamu Katoh, Gerald S. Werner, Nicolaus Reifart

Research output: Contribution to journal › Review article › peer-review

76 Scopus citations

Abstract

Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.

Original language	English (US)
Pages (from-to)	2692-2700
Number of pages	9
Journal	European heart journal
Volume	37
Issue number	35
DOIs	https://doi.org/10.1093/eurheartj/ehv391
State	Published - Sep 14 2016

Keywords

Cardiovascular outcome
Chronic total occlusion
Guidelines
PCI
Quality of life

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1093/eurheartj/ehv391

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Galassi, A. R., Brilakis, E. S., Boukhris, M., Tomasello, S. D., Sianos, G., Karmpaliotis, D., Di Mario, C., Strauss, B. H., Rinfret, S., Yamane, M., Katoh, O., Werner, G. S., & Reifart, N. (2016). Appropriateness of percutaneous revascularization of coronary chronic total occlusions: An overview. European heart journal, 37(35), 2692-2700. https://doi.org/10.1093/eurheartj/ehv391

Galassi, AR, Brilakis, ES, Boukhris, M, Tomasello, SD, Sianos, G, Karmpaliotis, D, Di Mario, C, Strauss, BH, Rinfret, S, Yamane, M, Katoh, O, Werner, GS & Reifart, N 2016, 'Appropriateness of percutaneous revascularization of coronary chronic total occlusions: An overview', European heart journal, vol. 37, no. 35, pp. 2692-2700. https://doi.org/10.1093/eurheartj/ehv391

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abstract = "Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.",

keywords = "Cardiovascular outcome, Chronic total occlusion, Guidelines, PCI, Quality of life",

author = "Galassi, {Alfredo R.} and Brilakis, {Emmanouil S.} and Marouane Boukhris and Tomasello, {Salvatore D.} and Georgios Sianos and Dimitri Karmpaliotis and {Di Mario}, Carlo and Strauss, {Bradley H.} and Stephane Rinfret and Masahisa Yamane and Osamu Katoh and Werner, {Gerald S.} and Nicolaus Reifart",

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AU - Galassi, Alfredo R.

AU - Brilakis, Emmanouil S.

AU - Boukhris, Marouane

AU - Tomasello, Salvatore D.

AU - Sianos, Georgios

AU - Karmpaliotis, Dimitri

AU - Di Mario, Carlo

AU - Strauss, Bradley H.

AU - Rinfret, Stephane

AU - Yamane, Masahisa

AU - Katoh, Osamu

AU - Werner, Gerald S.

AU - Reifart, Nicolaus

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N2 - Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.

AB - Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.

KW - Cardiovascular outcome

KW - Chronic total occlusion

KW - Guidelines

KW - PCI

KW - Quality of life

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Appropriateness of percutaneous revascularization of coronary chronic total occlusions: An overview

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Keywords

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