Arachidonate epoxygenase: Total synthesis of both enantiomers of 8,9- and 11,12-epoxyricosatrienoic acid

Paul Mosset, Pendri Yadagiri, Sun Lumin, Jorge Capdevila, J. R. Falck

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Both enantiomers of the epoxygenase metabolites 8,9- and 11,12-epoxyeicosatrienoic acid (EET) were synthesized by a convergent strategy utilizing dimethyl D- or L-malate and erythrospecific epoxidation.

Original languageEnglish (US)
Pages (from-to)6035-6038
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number50
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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