10 Citations (Scopus)

Abstract

Regional cerebral blood flow (rCBF) in the insular cortex (IC), a well-recognized site for central blood pressure (BP) modulation, is decreased at minute 10 during postexercise hypotension (PEH). PURPOSE: To determine whether exercise-induced decreases in IC rCBF are associated with BP changes throughout PEH. METHODS: Ten subjects were studied on three different days using a counterbalanced design with a randomized order for conditions; all were tested during a resting baseline and then at two of three time points postexercise: 10, 30, and 60 min. Data were collected for HR, mean BP, and rCBF using single-photon emission computed tomography as an index of brain activation. RESULTS: Using ANOVA across conditions, there were differences (P < 0.05; mean ± SD) for HR from baseline at minute 10 (+15 ± 4 bpm) and minute 30 (+6 ± 3 bpm) and for mean BP at minute 10 (-11 ± 4 mm Hg) and minute 30 (-5 ± 3 mm Hg). There were significant decreases (P < 0.05) in rCBF at both minutes 10 and 30 after exercise in the inferior thalamus and the right inferior IC regions. Although there were no decreases in BP or IC activity at minute 60, changes in right inferior posterior IC activity and BP were strongly correlated (r = 0.74; P < 0.05) postexercise. CONCLUSIONS: Findings show that exercise-induced decreases in IC and thalamic activity may be a significant neural factor contributing to at least the first 30 min of PEH.

Original languageEnglish (US)
Pages (from-to)574-580
Number of pages7
JournalMedicine and Science in Sports and Exercise
Volume41
Issue number3
DOIs
StatePublished - Mar 2009

Fingerprint

Post-Exercise Hypotension
Cerebrovascular Circulation
Regional Blood Flow
Cerebral Cortex
Blood Pressure
Single-Photon Emission-Computed Tomography
Thalamus
Analysis of Variance
Brain

Keywords

  • Autonomic nervous system
  • Brain mapping
  • Human
  • Magnetic resonance imaging (mri)
  • Single-photon emission computed tomography (spect)

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

@article{5cf0f05cf217453bb740d7de9e4e30e2,
title = "Are decreases in insular regional cerebral blood flow sustained during postexercise hypotension?",
abstract = "Regional cerebral blood flow (rCBF) in the insular cortex (IC), a well-recognized site for central blood pressure (BP) modulation, is decreased at minute 10 during postexercise hypotension (PEH). PURPOSE: To determine whether exercise-induced decreases in IC rCBF are associated with BP changes throughout PEH. METHODS: Ten subjects were studied on three different days using a counterbalanced design with a randomized order for conditions; all were tested during a resting baseline and then at two of three time points postexercise: 10, 30, and 60 min. Data were collected for HR, mean BP, and rCBF using single-photon emission computed tomography as an index of brain activation. RESULTS: Using ANOVA across conditions, there were differences (P < 0.05; mean ± SD) for HR from baseline at minute 10 (+15 ± 4 bpm) and minute 30 (+6 ± 3 bpm) and for mean BP at minute 10 (-11 ± 4 mm Hg) and minute 30 (-5 ± 3 mm Hg). There were significant decreases (P < 0.05) in rCBF at both minutes 10 and 30 after exercise in the inferior thalamus and the right inferior IC regions. Although there were no decreases in BP or IC activity at minute 60, changes in right inferior posterior IC activity and BP were strongly correlated (r = 0.74; P < 0.05) postexercise. CONCLUSIONS: Findings show that exercise-induced decreases in IC and thalamic activity may be a significant neural factor contributing to at least the first 30 min of PEH.",
keywords = "Autonomic nervous system, Brain mapping, Human, Magnetic resonance imaging (mri), Single-photon emission computed tomography (spect)",
author = "Williamson, {Jon W.} and Ross Querry and Rodderick McColl and Dana Mathews",
year = "2009",
month = "3",
doi = "10.1249/MSS.0b013e31818b98c8",
language = "English (US)",
volume = "41",
pages = "574--580",
journal = "Medicine and Science in Sports and Exercise",
issn = "0195-9131",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Are decreases in insular regional cerebral blood flow sustained during postexercise hypotension?

AU - Williamson, Jon W.

AU - Querry, Ross

AU - McColl, Rodderick

AU - Mathews, Dana

PY - 2009/3

Y1 - 2009/3

N2 - Regional cerebral blood flow (rCBF) in the insular cortex (IC), a well-recognized site for central blood pressure (BP) modulation, is decreased at minute 10 during postexercise hypotension (PEH). PURPOSE: To determine whether exercise-induced decreases in IC rCBF are associated with BP changes throughout PEH. METHODS: Ten subjects were studied on three different days using a counterbalanced design with a randomized order for conditions; all were tested during a resting baseline and then at two of three time points postexercise: 10, 30, and 60 min. Data were collected for HR, mean BP, and rCBF using single-photon emission computed tomography as an index of brain activation. RESULTS: Using ANOVA across conditions, there were differences (P < 0.05; mean ± SD) for HR from baseline at minute 10 (+15 ± 4 bpm) and minute 30 (+6 ± 3 bpm) and for mean BP at minute 10 (-11 ± 4 mm Hg) and minute 30 (-5 ± 3 mm Hg). There were significant decreases (P < 0.05) in rCBF at both minutes 10 and 30 after exercise in the inferior thalamus and the right inferior IC regions. Although there were no decreases in BP or IC activity at minute 60, changes in right inferior posterior IC activity and BP were strongly correlated (r = 0.74; P < 0.05) postexercise. CONCLUSIONS: Findings show that exercise-induced decreases in IC and thalamic activity may be a significant neural factor contributing to at least the first 30 min of PEH.

AB - Regional cerebral blood flow (rCBF) in the insular cortex (IC), a well-recognized site for central blood pressure (BP) modulation, is decreased at minute 10 during postexercise hypotension (PEH). PURPOSE: To determine whether exercise-induced decreases in IC rCBF are associated with BP changes throughout PEH. METHODS: Ten subjects were studied on three different days using a counterbalanced design with a randomized order for conditions; all were tested during a resting baseline and then at two of three time points postexercise: 10, 30, and 60 min. Data were collected for HR, mean BP, and rCBF using single-photon emission computed tomography as an index of brain activation. RESULTS: Using ANOVA across conditions, there were differences (P < 0.05; mean ± SD) for HR from baseline at minute 10 (+15 ± 4 bpm) and minute 30 (+6 ± 3 bpm) and for mean BP at minute 10 (-11 ± 4 mm Hg) and minute 30 (-5 ± 3 mm Hg). There were significant decreases (P < 0.05) in rCBF at both minutes 10 and 30 after exercise in the inferior thalamus and the right inferior IC regions. Although there were no decreases in BP or IC activity at minute 60, changes in right inferior posterior IC activity and BP were strongly correlated (r = 0.74; P < 0.05) postexercise. CONCLUSIONS: Findings show that exercise-induced decreases in IC and thalamic activity may be a significant neural factor contributing to at least the first 30 min of PEH.

KW - Autonomic nervous system

KW - Brain mapping

KW - Human

KW - Magnetic resonance imaging (mri)

KW - Single-photon emission computed tomography (spect)

UR - http://www.scopus.com/inward/record.url?scp=66149145930&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=66149145930&partnerID=8YFLogxK

U2 - 10.1249/MSS.0b013e31818b98c8

DO - 10.1249/MSS.0b013e31818b98c8

M3 - Article

C2 - 19204594

AN - SCOPUS:66149145930

VL - 41

SP - 574

EP - 580

JO - Medicine and Science in Sports and Exercise

JF - Medicine and Science in Sports and Exercise

SN - 0195-9131

IS - 3

ER -