Are more screws better? A systematic review of anchor density and curve correction in adolescent idiopathic scoliosis

A. Noelle Larson, Carl Eric Aubin, David W. Polly, Charles G T Ledonio, Baron S. Lonner, Suken A. Shah, B. Stephens Richards, Mark A. Erickson, John B. Emans, Stuart L. Weinstein

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Study Design: Systematic review of clinical studies. Objectives: To critically evaluate existing literature to determine whether increased anchor or implant density (screws, wires, and hooks per level fused) results in improved curve correction for adolescent idiopathic scoliosis (AIS) surgery. Summary of Background Data: Wide variability exists in the number of screws used for AIS surgery. High numbers of pedicle screws are increasingly used, but there is limited evidence to support this as best practice. Methods: Online English-language databases were searched to identify articles addressing anchor density. Articles were reviewed for anchor type/number, radiographic measures, and patient-reported outcomes. Results: Of 196 references identified, 10 studies totaling 929 patients met the inclusion criteria. Reported mean anchor density varied from 1.06 to 2.0 implants per level fused. Mean percent coronal curve correction varied from 64% to 70%. Two studies (463 patients) analyzed hook, hybrid (combined hooks and screws), and screw constructs as a single cohort. Both found increased correction with high-density constructs (p =.01, p <.001), perhaps as a result of the hooks and hybrid constructs. Eight retrospective studies and 1 prospective randomized, controlled trial had predominantly screw constructs (466 patients). Increased anchor density was not associated with improved curve correction. The studies evaluating screw density are significantly underpowered to detect a difference in curve correction. Conclusions: Wide heterogeneity in anchor density exists in the surgical treatment of AIS. Reports evaluating the effects of increased anchor density are mostly retrospective and significantly underpowered to detect a difference in curve correction and patient outcomes. At this time, there is insufficient evidence to show that anchor density affects clinical outcomes in AIS.

Original languageEnglish (US)
Pages (from-to)237-247
Number of pages11
JournalSpine Deformity
Volume1
Issue number4
DOIs
StatePublished - 2013

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Scoliosis
Practice Guidelines
Language
Randomized Controlled Trials
Retrospective Studies
Databases
Therapeutics

Keywords

  • Anchor point
  • Curve correction
  • Implant
  • Scoliosis
  • Screw

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Larson, A. N., Aubin, C. E., Polly, D. W., Ledonio, C. G. T., Lonner, B. S., Shah, S. A., ... Weinstein, S. L. (2013). Are more screws better? A systematic review of anchor density and curve correction in adolescent idiopathic scoliosis. Spine Deformity, 1(4), 237-247. https://doi.org/10.1016/j.jspd.2013.05.009

Are more screws better? A systematic review of anchor density and curve correction in adolescent idiopathic scoliosis. / Larson, A. Noelle; Aubin, Carl Eric; Polly, David W.; Ledonio, Charles G T; Lonner, Baron S.; Shah, Suken A.; Richards, B. Stephens; Erickson, Mark A.; Emans, John B.; Weinstein, Stuart L.

In: Spine Deformity, Vol. 1, No. 4, 2013, p. 237-247.

Research output: Contribution to journalArticle

Larson, AN, Aubin, CE, Polly, DW, Ledonio, CGT, Lonner, BS, Shah, SA, Richards, BS, Erickson, MA, Emans, JB & Weinstein, SL 2013, 'Are more screws better? A systematic review of anchor density and curve correction in adolescent idiopathic scoliosis', Spine Deformity, vol. 1, no. 4, pp. 237-247. https://doi.org/10.1016/j.jspd.2013.05.009
Larson, A. Noelle ; Aubin, Carl Eric ; Polly, David W. ; Ledonio, Charles G T ; Lonner, Baron S. ; Shah, Suken A. ; Richards, B. Stephens ; Erickson, Mark A. ; Emans, John B. ; Weinstein, Stuart L. / Are more screws better? A systematic review of anchor density and curve correction in adolescent idiopathic scoliosis. In: Spine Deformity. 2013 ; Vol. 1, No. 4. pp. 237-247.
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abstract = "Study Design: Systematic review of clinical studies. Objectives: To critically evaluate existing literature to determine whether increased anchor or implant density (screws, wires, and hooks per level fused) results in improved curve correction for adolescent idiopathic scoliosis (AIS) surgery. Summary of Background Data: Wide variability exists in the number of screws used for AIS surgery. High numbers of pedicle screws are increasingly used, but there is limited evidence to support this as best practice. Methods: Online English-language databases were searched to identify articles addressing anchor density. Articles were reviewed for anchor type/number, radiographic measures, and patient-reported outcomes. Results: Of 196 references identified, 10 studies totaling 929 patients met the inclusion criteria. Reported mean anchor density varied from 1.06 to 2.0 implants per level fused. Mean percent coronal curve correction varied from 64{\%} to 70{\%}. Two studies (463 patients) analyzed hook, hybrid (combined hooks and screws), and screw constructs as a single cohort. Both found increased correction with high-density constructs (p =.01, p <.001), perhaps as a result of the hooks and hybrid constructs. Eight retrospective studies and 1 prospective randomized, controlled trial had predominantly screw constructs (466 patients). Increased anchor density was not associated with improved curve correction. The studies evaluating screw density are significantly underpowered to detect a difference in curve correction. Conclusions: Wide heterogeneity in anchor density exists in the surgical treatment of AIS. Reports evaluating the effects of increased anchor density are mostly retrospective and significantly underpowered to detect a difference in curve correction and patient outcomes. At this time, there is insufficient evidence to show that anchor density affects clinical outcomes in AIS.",
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AU - Larson, A. Noelle

AU - Aubin, Carl Eric

AU - Polly, David W.

AU - Ledonio, Charles G T

AU - Lonner, Baron S.

AU - Shah, Suken A.

AU - Richards, B. Stephens

AU - Erickson, Mark A.

AU - Emans, John B.

AU - Weinstein, Stuart L.

PY - 2013

Y1 - 2013

N2 - Study Design: Systematic review of clinical studies. Objectives: To critically evaluate existing literature to determine whether increased anchor or implant density (screws, wires, and hooks per level fused) results in improved curve correction for adolescent idiopathic scoliosis (AIS) surgery. Summary of Background Data: Wide variability exists in the number of screws used for AIS surgery. High numbers of pedicle screws are increasingly used, but there is limited evidence to support this as best practice. Methods: Online English-language databases were searched to identify articles addressing anchor density. Articles were reviewed for anchor type/number, radiographic measures, and patient-reported outcomes. Results: Of 196 references identified, 10 studies totaling 929 patients met the inclusion criteria. Reported mean anchor density varied from 1.06 to 2.0 implants per level fused. Mean percent coronal curve correction varied from 64% to 70%. Two studies (463 patients) analyzed hook, hybrid (combined hooks and screws), and screw constructs as a single cohort. Both found increased correction with high-density constructs (p =.01, p <.001), perhaps as a result of the hooks and hybrid constructs. Eight retrospective studies and 1 prospective randomized, controlled trial had predominantly screw constructs (466 patients). Increased anchor density was not associated with improved curve correction. The studies evaluating screw density are significantly underpowered to detect a difference in curve correction. Conclusions: Wide heterogeneity in anchor density exists in the surgical treatment of AIS. Reports evaluating the effects of increased anchor density are mostly retrospective and significantly underpowered to detect a difference in curve correction and patient outcomes. At this time, there is insufficient evidence to show that anchor density affects clinical outcomes in AIS.

AB - Study Design: Systematic review of clinical studies. Objectives: To critically evaluate existing literature to determine whether increased anchor or implant density (screws, wires, and hooks per level fused) results in improved curve correction for adolescent idiopathic scoliosis (AIS) surgery. Summary of Background Data: Wide variability exists in the number of screws used for AIS surgery. High numbers of pedicle screws are increasingly used, but there is limited evidence to support this as best practice. Methods: Online English-language databases were searched to identify articles addressing anchor density. Articles were reviewed for anchor type/number, radiographic measures, and patient-reported outcomes. Results: Of 196 references identified, 10 studies totaling 929 patients met the inclusion criteria. Reported mean anchor density varied from 1.06 to 2.0 implants per level fused. Mean percent coronal curve correction varied from 64% to 70%. Two studies (463 patients) analyzed hook, hybrid (combined hooks and screws), and screw constructs as a single cohort. Both found increased correction with high-density constructs (p =.01, p <.001), perhaps as a result of the hooks and hybrid constructs. Eight retrospective studies and 1 prospective randomized, controlled trial had predominantly screw constructs (466 patients). Increased anchor density was not associated with improved curve correction. The studies evaluating screw density are significantly underpowered to detect a difference in curve correction. Conclusions: Wide heterogeneity in anchor density exists in the surgical treatment of AIS. Reports evaluating the effects of increased anchor density are mostly retrospective and significantly underpowered to detect a difference in curve correction and patient outcomes. At this time, there is insufficient evidence to show that anchor density affects clinical outcomes in AIS.

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KW - Curve correction

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