Are psychotropic drugs safe to use during pregnancy?

Asim A. Shah, Imran S. Khawaja, Awais Aftab

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Most psychotropics are currently given a US Food and Drug Adminstration (FDA) drug rating of category C, meaning there is evidence of potential risk to a fetus. Some psychotropics, however, have a higher degree of risk to the fetus than others, and this article discusses the use of those psychotropics for which caution is warranted based on currently available evidence and clinical opinion. The psychotropics that will be highlighted here include paroxetine, monoamine oxidase inhibitors, lithium, valproate, carbamazepine, and benzodiazepines. We suggest caution with regards to their routine use or as a first-line treatment in pregnancy. Five benzodiazepines are category X according to the FDA and are therefore contraindicated in pregnancy. For all these medications it is important not to overlook the benefits of psychiatric stability from continued treatment and the harms of discontinuation, which include increased risk of relapse of the illness.

Original languageEnglish (US)
Pages (from-to)71-76
Number of pages6
JournalPsychiatric Annals
Volume45
Issue number2
DOIs
StatePublished - Jan 1 2015

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Psychotropic Drugs
Benzodiazepines
Pregnancy
Fetus
Pharmaceutical Preparations
Food
Paroxetine
Monoamine Oxidase Inhibitors
Carbamazepine
Valproic Acid
Lithium
Psychiatry
Recurrence

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Are psychotropic drugs safe to use during pregnancy? / Shah, Asim A.; Khawaja, Imran S.; Aftab, Awais.

In: Psychiatric Annals, Vol. 45, No. 2, 01.01.2015, p. 71-76.

Research output: Contribution to journalArticle

Shah, Asim A. ; Khawaja, Imran S. ; Aftab, Awais. / Are psychotropic drugs safe to use during pregnancy?. In: Psychiatric Annals. 2015 ; Vol. 45, No. 2. pp. 71-76.
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