Are short telomeres predictive of advanced cancer?

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The combination of variable telomere length in cancer cells and shorter telomere length in cancerassociated stromal cells strongly correlates with progression to prostate cancer metastasis and cancer death. The implication is that telomere length measurements have potential not only as prognostic indicators of prostate cancer outcomes but also as risk stratification enrichment biomarkers for individualized therapeutic interventions.

Original languageEnglish (US)
Pages (from-to)1096-1098
Number of pages3
JournalCancer Discovery
Volume3
Issue number10
DOIs
StatePublished - Oct 2013

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Telomere
Prostatic Neoplasms
Neoplasms
Stromal Cells
Biomarkers
Neoplasm Metastasis
Therapeutics

ASJC Scopus subject areas

  • Oncology

Cite this

Are short telomeres predictive of advanced cancer? / Shay, Jerry W.

In: Cancer Discovery, Vol. 3, No. 10, 10.2013, p. 1096-1098.

Research output: Contribution to journalArticle

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