Arterial spin-labeling in routine clinical practice, part 1: Technique and artifacts

A. R. Deibler, J. M. Pollock, R. A. Kraft, H. Tan, J. H. Burdette, Joseph A Maldjian

Research output: Contribution to journalReview article

175 Citations (Scopus)

Abstract

The routine use of arterial spin-labeling (ASL) in a clinical population has led to the depiction of diverse brain pathologic features. Unique challenges in the acquisition, postprocessing, and analysis of cerebral blood flow (CBF) maps are encountered in such a population, and high-quality ASL CBF maps can be generated consistently with attention to quality control and with the use of a dedicated postprocessing pipeline. Familiarity with commonly encountered artifacts can help avoid pitfalls in the interpretation of CBF maps. The purpose of this review was to describe our experience with a heterogeneous collection of ASL perfusion cases with an emphasis on methodology and common artifacts encountered with the technique. In a period of 1 year, more than 3000 pulsed ASL cases were performed as a component of routine clinical brain MR evaluation at both 1.5 and 3T. These ASL studies were analyzed with respect to overall image quality and patterns of perfusion on final gray-scale DICOM images and color Joint Photographic Experts Group (JPEG) CBF maps, and common artifacts and their impact on final image quality were categorized.

Original languageEnglish (US)
Pages (from-to)1228-1234
Number of pages7
JournalAmerican Journal of Neuroradiology
Volume29
Issue number7
DOIs
StatePublished - Aug 1 2008

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Cerebrovascular Circulation
Artifacts
Perfusion
Brain
Quality Control
Population
Color

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Arterial spin-labeling in routine clinical practice, part 1 : Technique and artifacts. / Deibler, A. R.; Pollock, J. M.; Kraft, R. A.; Tan, H.; Burdette, J. H.; Maldjian, Joseph A.

In: American Journal of Neuroradiology, Vol. 29, No. 7, 01.08.2008, p. 1228-1234.

Research output: Contribution to journalReview article

Deibler, A. R. ; Pollock, J. M. ; Kraft, R. A. ; Tan, H. ; Burdette, J. H. ; Maldjian, Joseph A. / Arterial spin-labeling in routine clinical practice, part 1 : Technique and artifacts. In: American Journal of Neuroradiology. 2008 ; Vol. 29, No. 7. pp. 1228-1234.
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