Assembly of chick brain tubulin onto isolated basal bodies of Chlamydomonas reinhardi

W. J. Snell, W. L. Dentler, L. T. Haimo, L. I. Binder, J. L. Rosenbaum

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

Basal bodies isolated from Chlamydomonas reinhardi will serve as initiation centers for the assembly of chick brain microtubule protein subunits (tubulin) into microtubules. The rate of microtubule assembly is tubulin-concentration dependent; this assembly occurs onto both distal and proximal ends of the basal body microtubules, with distal assembly greatly favored. In vitro assembly of brain tubulin also occurs onto the mid-lateral aspects of the basal bodies, presumably onto the fiber connecting the two basal bodies.

Original languageEnglish (US)
Pages (from-to)357-360
Number of pages4
JournalScience
Volume185
Issue number4148
DOIs
StatePublished - Jan 1 1974

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