TY - JOUR
T1 - Assessing the global threat from Zika virus
AU - Lessler, Justin
AU - Chaisson, Lelia H.
AU - Kucirka, Lauren M.
AU - Bi, Qifang
AU - Grantz, Kyra
AU - Salje, Henrik
AU - Carcelen, Andrea C.
AU - Ott, Cassandra T.
AU - Sheffield, Jeanne S.
AU - Ferguson, Neil M.
AU - Cummings, Derek A T
AU - Metcalf, C. Jessica E
AU - Rodriguez-Barraquer, Isabel
PY - 2016/8/12
Y1 - 2016/8/12
N2 - First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key factors that determine the extent of the global threat from ZIKV infection and resulting complications. Here, we review what is known about the epidemiology, natural history, and public health effects of ZIKV infection, the empirical basis for this knowledge, and the critical knowledge gaps that need to be filled.
AB - First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key factors that determine the extent of the global threat from ZIKV infection and resulting complications. Here, we review what is known about the epidemiology, natural history, and public health effects of ZIKV infection, the empirical basis for this knowledge, and the critical knowledge gaps that need to be filled.
UR - http://www.scopus.com/inward/record.url?scp=84978898104&partnerID=8YFLogxK
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U2 - 10.1126/science.aaf8160
DO - 10.1126/science.aaf8160
M3 - Review article
C2 - 27417495
AN - SCOPUS:84978898104
SN - 0036-8075
VL - 353
JO - Science
JF - Science
IS - 6300
ER -