Assessment of a noninvasive optical photoplethysmography imaging device with dynamic tissue phantom models

C. Ikenna Nwafor, Kevin D. Plant, Darlene R. King, Brian P. McCall, John J. Squiers, Wensheng Fan, J. Michael Dimaio, Jeffrey E. Thatcher

Research output: Contribution to journalArticle

Abstract

Noncontact photoplethysmography (PPG) has been studied as a method to provide low-cost, noninvasive, two-dimensional blood oxygenation measurements and medical imaging for a variety of near-surface pathologies. To evaluate this technology in a laboratory setting, dynamic tissue phantoms were developed with tunable parameters that mimic physiologic properties of the skin, including blood vessel volume change, pulse wave frequency, and tissue scattering and absorption. Tissue phantoms were generated using an elastic tubing to represent a blood vessel where the luminal volume could be modulated with a pulsatile fluid flow. The blood was mimicked with a scattering and absorbing motility standard, and the tissue with a gelatin-lipid emulsion hydrogel. A noncontact PPG imaging system was then evaluated using the phantoms. Noncontact PPG imaging accurately identified pulse frequency, and PPG signals from these phantoms suggest that the phantoms can be used to evaluate noncontact PPG imaging systems. Such information may be valuable to the development of future PPG imaging systems.

Original languageEnglish (US)
Article number096003
JournalJournal of Biomedical Optics
Volume22
Issue number9
DOIs
StatePublished - Sep 1 2017

Fingerprint

Photoplethysmography
Tissue
Imaging techniques
blood vessels
Imaging systems
blood
Blood vessels
locomotion
oxygenation
gelatins
pathology
Blood
pulses
scattering
Scattering
emulsions
fluid flow
lipids
Oxygenation
Hydrogel

Keywords

  • medical imaging
  • photoplethysmography
  • tissue phantom

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Biomedical Engineering

Cite this

Nwafor, C. I., Plant, K. D., King, D. R., McCall, B. P., Squiers, J. J., Fan, W., ... Thatcher, J. E. (2017). Assessment of a noninvasive optical photoplethysmography imaging device with dynamic tissue phantom models. Journal of Biomedical Optics, 22(9), [096003]. https://doi.org/10.1117/1.JBO.22.9.096003

Assessment of a noninvasive optical photoplethysmography imaging device with dynamic tissue phantom models. / Nwafor, C. Ikenna; Plant, Kevin D.; King, Darlene R.; McCall, Brian P.; Squiers, John J.; Fan, Wensheng; Dimaio, J. Michael; Thatcher, Jeffrey E.

In: Journal of Biomedical Optics, Vol. 22, No. 9, 096003, 01.09.2017.

Research output: Contribution to journalArticle

Nwafor, CI, Plant, KD, King, DR, McCall, BP, Squiers, JJ, Fan, W, Dimaio, JM & Thatcher, JE 2017, 'Assessment of a noninvasive optical photoplethysmography imaging device with dynamic tissue phantom models', Journal of Biomedical Optics, vol. 22, no. 9, 096003. https://doi.org/10.1117/1.JBO.22.9.096003
Nwafor, C. Ikenna ; Plant, Kevin D. ; King, Darlene R. ; McCall, Brian P. ; Squiers, John J. ; Fan, Wensheng ; Dimaio, J. Michael ; Thatcher, Jeffrey E. / Assessment of a noninvasive optical photoplethysmography imaging device with dynamic tissue phantom models. In: Journal of Biomedical Optics. 2017 ; Vol. 22, No. 9.
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