Assisted reproductive technology

Experience with IVF/ICSI

Javed Haider Rizvi, Nadeem Faiyaz Zuberi, Saifullah Bhatti, Muniza Bana, Sadia Virk, Shahnaz Nadir, Atiya Kidwai, Nasreen Tahir

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: To analyze success rates of assisted reproduction techniques ART (IVF/ICSI) in couples experiencing subfertility, and factors which may help in predicting treatment outcome. Design: A prospective cohort follow-up study. Place and Duration of Study: Study was conducted at Concept Fertility Centre, Karachi, between July 1, 2000 and December 31, 2002. Subjects and Methods: A cohort of 310 couples undergoing 330in-vitro fertilization (IVF) and intra cytoplasmic sperm injection (ICSI) cycles were followed for treatment outcomes. Predictor variables included age of women, cause of subfertility, drug regimen used for ovulation induction, day of embryo transfer, and ease of embryo transfer. While outcome variables included rates of fertilization, pregnancy, live birth, miscarriages, multiple pregnancies and ovarian hyperstimulation syndrome (OHSS). Results: The overall pregnancy rate was 35.2 %, while takehome live-birth rate was 25.1%. Treatment cycles which were done for male factor only, had higher probability of success as compared to female factors or for unexplained infertility. Patients who underwent transvaginal ovum pick up and embryo transfer (TVOPU + ET) had an overall pregnancy rate of 29.4% as compared to those who underwent frozen embryo transfer (FET) cycles (22.6%). There was no statistically significant difference between pregnancy rates for ovulation induction with recumbent FSH (rFSH) and HMG (32.7% v 33.6%, p-value 0.87). Quality of embryo transfer was significantly better (33.7%, v 24.2%, p-value 0.042) in patients who conceived. Conclusion: Our results are comparable in terms of pregnancy rates, live birth rates and complication rates, to the results reported in international literature. We however, need more data from centres in Pakistan for future reference and research.

Original languageEnglish (US)
Pages (from-to)270-273
Number of pages4
JournalJournal of the College of Physicians and Surgeons Pakistan
Volume14
Issue number5
StatePublished - May 1 2004

Fingerprint

Assisted Reproductive Techniques
Embryo Transfer
Pregnancy Rate
Spermatozoa
Injections
Infertility
Ovulation Induction
Birth Rate
Fertilization
Ovarian Hyperstimulation Syndrome
Reproductive Techniques
Multiple Pregnancy
Pakistan
Live Birth
Spontaneous Abortion
Ovum
Fertility
Research
Pharmaceutical Preparations

Keywords

  • Assisted reproductive techniques
  • In-Vitro fertilization
  • Intra cytoplasmic sperm injection (ICSI)
  • Pakistan

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Rizvi, J. H., Zuberi, N. F., Bhatti, S., Bana, M., Virk, S., Nadir, S., ... Tahir, N. (2004). Assisted reproductive technology: Experience with IVF/ICSI. Journal of the College of Physicians and Surgeons Pakistan, 14(5), 270-273.

Assisted reproductive technology : Experience with IVF/ICSI. / Rizvi, Javed Haider; Zuberi, Nadeem Faiyaz; Bhatti, Saifullah; Bana, Muniza; Virk, Sadia; Nadir, Shahnaz; Kidwai, Atiya; Tahir, Nasreen.

In: Journal of the College of Physicians and Surgeons Pakistan, Vol. 14, No. 5, 01.05.2004, p. 270-273.

Research output: Contribution to journalArticle

Rizvi, JH, Zuberi, NF, Bhatti, S, Bana, M, Virk, S, Nadir, S, Kidwai, A & Tahir, N 2004, 'Assisted reproductive technology: Experience with IVF/ICSI', Journal of the College of Physicians and Surgeons Pakistan, vol. 14, no. 5, pp. 270-273.
Rizvi JH, Zuberi NF, Bhatti S, Bana M, Virk S, Nadir S et al. Assisted reproductive technology: Experience with IVF/ICSI. Journal of the College of Physicians and Surgeons Pakistan. 2004 May 1;14(5):270-273.
Rizvi, Javed Haider ; Zuberi, Nadeem Faiyaz ; Bhatti, Saifullah ; Bana, Muniza ; Virk, Sadia ; Nadir, Shahnaz ; Kidwai, Atiya ; Tahir, Nasreen. / Assisted reproductive technology : Experience with IVF/ICSI. In: Journal of the College of Physicians and Surgeons Pakistan. 2004 ; Vol. 14, No. 5. pp. 270-273.
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