TY - JOUR
T1 - Association between cardiorespiratory fitness and accelerometer-derived physical activity and sedentary time in the general population
AU - Kulinski, Jacquelyn P.
AU - Khera, Amit
AU - Ayers, Colby R.
AU - Das, Sandeep R
AU - de Lemos, James A
AU - Blair, Steven N.
AU - Berry, Jarett D
N1 - Funding Information:
Potential Competing Interests: Dr De Lemos has received honoraria from Astra Zeneca, consulting income from Janssen Pharmaceuticals, and serves on a Data Safety Monitoring Board for Novo Nordisk. Dr Berry is a member of the Speaker's Bureau for Merck & Co. Dr Blair serves on advisory boards for Technogym, Santech, and the Clarity Project; receives book royalties from Human Kinetics; and has unrestricted research grants from the Coca-Cola Company, Body Media, Technogym, and the National Institutes of Health.
Funding Information:
Grant Support: The work was supported by a grant (J.D.B.) from the Dedman Family Scholar in Clinical Care endowment at the University of Texas Southwestern Medical Center ; grant K23 HL092229 (J.D.B.) from the National Heart, Lung, and Blood Institute ; and grant 13GRNT14560079 (J.D.B.) from the American Heart Association .
PY - 2014/8
Y1 - 2014/8
N2 - Objective To determine the association between cardiorespiratory fitness and sedentary behavior, independent of exercise activity. Patients and Methods We included 2223 participants (aged 12-49 years; 1053 females [47%]) without known heart disease who had both cardiovascular fitness testing and at least 1 day of accelerometer data from the National Health and Nutrition Examination Survey 2003-2004. From accelerometer data, we quantified bouts of exercise as mean minutes per day for each participant. Sedentary time was defined as less than 100 counts per minute in mean minutes per day. Cardiorespiratory fitness was derived from a submaximal exercise treadmill test. Multivariable-adjusted linear regression analyses were performed with fitness as the dependent variable. Models were stratified by sex, adjusted for age, body mass index, and wear time, and included sedentary and exercise time. Results An additional hour of daily exercise activity time was associated with a 0.88 (0.37-1.39; P<.001) metabolic equivalent of task (MET) higher fitness for men and a 1.37 (0.43-2.31; P=.004) MET higher fitness for women. An additional hour of sedentary time was associated with a -0.12 (-0.02 to -0.22; P=.03) and a -0.24 (-0.10 to -0.38; P<.001) MET difference in fitness for men and women, respectively. Conclusion After adjustment for exercise activity, sedentary behavior appears to have an inverse association with fitness. These findings suggest that the risk related to sedentary behavior might be mediated, in part, through lower fitness levels.
AB - Objective To determine the association between cardiorespiratory fitness and sedentary behavior, independent of exercise activity. Patients and Methods We included 2223 participants (aged 12-49 years; 1053 females [47%]) without known heart disease who had both cardiovascular fitness testing and at least 1 day of accelerometer data from the National Health and Nutrition Examination Survey 2003-2004. From accelerometer data, we quantified bouts of exercise as mean minutes per day for each participant. Sedentary time was defined as less than 100 counts per minute in mean minutes per day. Cardiorespiratory fitness was derived from a submaximal exercise treadmill test. Multivariable-adjusted linear regression analyses were performed with fitness as the dependent variable. Models were stratified by sex, adjusted for age, body mass index, and wear time, and included sedentary and exercise time. Results An additional hour of daily exercise activity time was associated with a 0.88 (0.37-1.39; P<.001) metabolic equivalent of task (MET) higher fitness for men and a 1.37 (0.43-2.31; P=.004) MET higher fitness for women. An additional hour of sedentary time was associated with a -0.12 (-0.02 to -0.22; P=.03) and a -0.24 (-0.10 to -0.38; P<.001) MET difference in fitness for men and women, respectively. Conclusion After adjustment for exercise activity, sedentary behavior appears to have an inverse association with fitness. These findings suggest that the risk related to sedentary behavior might be mediated, in part, through lower fitness levels.
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U2 - 10.1016/j.mayocp.2014.04.019
DO - 10.1016/j.mayocp.2014.04.019
M3 - Article
C2 - 25012770
AN - SCOPUS:84905406953
SN - 0025-6196
VL - 89
SP - 1063
EP - 1071
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 8
ER -