Association of β-Lactam Allergy Documentation and Prophylactic Antibiotic Use in Surgery: A National Cross-Sectional Study of Hospitalized Patients

Christie M. Bertram, Michael Postelnick, Christian M. Mancini, Xiaoqing Fu, Yuqing Zhang, Lucas T. Schulz, Tanaya Bhowmick, Francesca Lee, Kimberly G. Blumenthal

Research output: Contribution to journalArticlepeer-review

Abstract

Alternative antibiotics for surgical prophylaxis are associated with increased adverse events and surgical site infection compared to cefazolin. In a sample of perioperative inpatients from 100 hospitals in the United States, cefazolin was 9-fold less likely to be used in patients with a documented β-lactam allergy whereas clindamycin was 45-fold more likely.

Original languageEnglish (US)
Pages (from-to)E872-E875
JournalClinical Infectious Diseases
Volume72
Issue number11
DOIs
StatePublished - Jun 1 2021

Keywords

  • allergy
  • antibiotic
  • surgical prophylaxis
  • β-lactam

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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