Association of extracranial carotid arterial disease, prior atherothrombotic brain infarction, systemic hypertension, and left ventricular hypertrophy with the incidence of now atherothrombotic brain infarction at 45-month follow-up in 1,482 older patients

Wilbert S. Aronow, Chul Ahn, Itzhak Kronzon, Hal Gutstein, Myron R. Schoenfeld

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Comparison of 239 older patients with 40% to 100% extracranial carotid arterial disease (ECAD) with 1,243 older patients with no significant ECAD showed a higher prevalence of systemic hypertension, left ventricular (LV) hypertrophy, and prior atherothrombotic brain infarction (ABI) and a higher incidence of new ABI in patients with ECAD than in patients without ECAD. A multivariate Cox regression model showed that independent predictors of new ABI were ECAD (risk ratio = 2.5), systemic hypertension (risk ratio = 2.3), prior ABI (risk ratio = 2.3), LV hypertrophy (risk ratio = 2.3), male sex (risk ratio = 1.3).

Original languageEnglish (US)
Pages (from-to)991-993
Number of pages3
JournalAmerican Journal of Cardiology
Volume79
Issue number7
DOIs
StatePublished - Apr 1 1997

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Brain Infarction
Carotid Artery Diseases
Left Ventricular Hypertrophy
Odds Ratio
Hypertension
Incidence
Sex Ratio
Proportional Hazards Models

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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abstract = "Comparison of 239 older patients with 40{\%} to 100{\%} extracranial carotid arterial disease (ECAD) with 1,243 older patients with no significant ECAD showed a higher prevalence of systemic hypertension, left ventricular (LV) hypertrophy, and prior atherothrombotic brain infarction (ABI) and a higher incidence of new ABI in patients with ECAD than in patients without ECAD. A multivariate Cox regression model showed that independent predictors of new ABI were ECAD (risk ratio = 2.5), systemic hypertension (risk ratio = 2.3), prior ABI (risk ratio = 2.3), LV hypertrophy (risk ratio = 2.3), male sex (risk ratio = 1.3).",
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AU - Ahn, Chul

AU - Kronzon, Itzhak

AU - Gutstein, Hal

AU - Schoenfeld, Myron R.

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