Asymmetric synthesis of tertiary benzylic alcohols

Monika I. Antczak, Feng Cai, Joseph M. Ready

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Vinyl, aryl, and alkynyl organometallics add to ketones containing a stereogenic sulfoxide. Tertiary alcohols are generated in diastereomerically and enantiomerically pure form. Reductive lithiation converts the sulfoxide into a variety of useful functional groups.

Original languageEnglish (US)
Pages (from-to)184-187
Number of pages4
JournalOrganic Letters
Volume13
Issue number2
DOIs
StatePublished - Jan 21 2011

Fingerprint

sulfoxide
ketones
alcohols
Alcohols
Organometallics
synthesis
Ketones
Functional groups

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Asymmetric synthesis of tertiary benzylic alcohols. / Antczak, Monika I.; Cai, Feng; Ready, Joseph M.

In: Organic Letters, Vol. 13, No. 2, 21.01.2011, p. 184-187.

Research output: Contribution to journalArticle

Antczak, Monika I. ; Cai, Feng ; Ready, Joseph M. / Asymmetric synthesis of tertiary benzylic alcohols. In: Organic Letters. 2011 ; Vol. 13, No. 2. pp. 184-187.
@article{6562cf36e15a4afba89b3b1577f2b108,
title = "Asymmetric synthesis of tertiary benzylic alcohols",
abstract = "Vinyl, aryl, and alkynyl organometallics add to ketones containing a stereogenic sulfoxide. Tertiary alcohols are generated in diastereomerically and enantiomerically pure form. Reductive lithiation converts the sulfoxide into a variety of useful functional groups.",
author = "Antczak, {Monika I.} and Feng Cai and Ready, {Joseph M.}",
year = "2011",
month = "1",
day = "21",
doi = "10.1021/ol102567h",
language = "English (US)",
volume = "13",
pages = "184--187",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "2",

}

TY - JOUR

T1 - Asymmetric synthesis of tertiary benzylic alcohols

AU - Antczak, Monika I.

AU - Cai, Feng

AU - Ready, Joseph M.

PY - 2011/1/21

Y1 - 2011/1/21

N2 - Vinyl, aryl, and alkynyl organometallics add to ketones containing a stereogenic sulfoxide. Tertiary alcohols are generated in diastereomerically and enantiomerically pure form. Reductive lithiation converts the sulfoxide into a variety of useful functional groups.

AB - Vinyl, aryl, and alkynyl organometallics add to ketones containing a stereogenic sulfoxide. Tertiary alcohols are generated in diastereomerically and enantiomerically pure form. Reductive lithiation converts the sulfoxide into a variety of useful functional groups.

UR - http://www.scopus.com/inward/record.url?scp=78651483958&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78651483958&partnerID=8YFLogxK

U2 - 10.1021/ol102567h

DO - 10.1021/ol102567h

M3 - Article

VL - 13

SP - 184

EP - 187

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 2

ER -