Atherosclerotic Renal Arterial Stenosis: Clinical Outcomes of Stent Placement for Hypertension and Renal Failure

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Abstract

The authors performed primary stent placement in 100 patients with atherosclerotic renal arterial stenosis to determine the technical success rate and long-term clinical outcome. Twenty-five patients had resistant hypertension, 50 had impaired renal function and 25 had both. Angiography was used to evaluate immediate technical results. Serial systolic and diastolic blood pressure and serum creatinine values were reviewed to assess clinical outcomes. Follow up continued every 6 months after the procedure and results were compared with those obtained at the time of the procedure. The result was a 95.2% technical success rate. Of 48 patents, resistant hypertension was improved in 38, cured in two, but failed to respond in 8 patients. Mean blood pressures (systolic and diastolic) were significantly lower through follow-up at 30 months than before the procedure. In the 65 patients treated for renal impairment, function stabilized in 25, improved in 20, and continued to deteriorate in 20. Complications occurred in 18 cases, of which 8 were major and included 2 procedure-related deaths. The authors concluded that primary stent placement for resistant hypertension and recovery of renal function has a high technical success rate and produces clinical benefits in most patients.

Original languageEnglish (US)
Pages (from-to)80-81
Number of pages2
JournalPerspectives in Vascular Surgery and Endovascular Therapy
Volume16
Issue number1
DOIs
StatePublished - 2004

Fingerprint

Stents
Renal Insufficiency
Pathologic Constriction
Hypertension
Kidney
Blood Pressure
Renal Hypertension
Patents
Recovery of Function
Creatinine
Angiography
Serum

Keywords

  • angiography
  • atherosclerotic renal arterial stenosis
  • hypertension
  • renal artery
  • stent

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Atherosclerotic Renal Arterial Stenosis: Clinical Outcomes of Stent Placement for Hypertension and Renal Failure",
abstract = "The authors performed primary stent placement in 100 patients with atherosclerotic renal arterial stenosis to determine the technical success rate and long-term clinical outcome. Twenty-five patients had resistant hypertension, 50 had impaired renal function and 25 had both. Angiography was used to evaluate immediate technical results. Serial systolic and diastolic blood pressure and serum creatinine values were reviewed to assess clinical outcomes. Follow up continued every 6 months after the procedure and results were compared with those obtained at the time of the procedure. The result was a 95.2{\%} technical success rate. Of 48 patents, resistant hypertension was improved in 38, cured in two, but failed to respond in 8 patients. Mean blood pressures (systolic and diastolic) were significantly lower through follow-up at 30 months than before the procedure. In the 65 patients treated for renal impairment, function stabilized in 25, improved in 20, and continued to deteriorate in 20. Complications occurred in 18 cases, of which 8 were major and included 2 procedure-related deaths. The authors concluded that primary stent placement for resistant hypertension and recovery of renal function has a high technical success rate and produces clinical benefits in most patients.",
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