Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy

Kartik R. Kumar, Swati N. Mandleywala, Mark S. Link

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations in genes coding for cardiac sarcomeres. HCM is the most common inherited heart disease, with a prevalence of 0.2%. There are multiple genetic variants that cause pleomorphic clinical attributes and disease characterized by myocardial disarray and myocardial hypertrophy. Patients are at an increased risk of atrial and ventricular arrhythmias. Management of these arrhythmias is complex. Atrial fibrillation is associated with increased mortality and thromboembolism. Ventricular arrhythmias are life threatening and best treated with an implantable defibrillator.

Original languageEnglish (US)
Pages (from-to)173-186
Number of pages14
JournalCardiac Electrophysiology Clinics
Volume7
Issue number2
DOIs
StatePublished - Jan 1 2015

Fingerprint

Hypertrophic Cardiomyopathy
Cardiac Arrhythmias
Disease Attributes
Sarcomeres
Implantable Defibrillators
Thromboembolism
Cardiomyopathies
Atrial Fibrillation
Hypertrophy
Heart Diseases
Mutation
Mortality
Genes

Keywords

  • Arrhythmias
  • Atrial fibrillation
  • Electrophysiology
  • Hypertrophic cardiomyopathy
  • Risk factors
  • Ventricular fibrillation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy. / Kumar, Kartik R.; Mandleywala, Swati N.; Link, Mark S.

In: Cardiac Electrophysiology Clinics, Vol. 7, No. 2, 01.01.2015, p. 173-186.

Research output: Contribution to journalReview article

Kumar, Kartik R. ; Mandleywala, Swati N. ; Link, Mark S. / Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy. In: Cardiac Electrophysiology Clinics. 2015 ; Vol. 7, No. 2. pp. 173-186.
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