Atypical teratoid/rhabdoid tumor: Cytology and differential diagnosis in adults

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Abstract

Atypical teratoid/rhabdoid tumors (AT/RTs) are malignant intracranial neoplasms that usually occur in the posterior fossa of children. They are characterized by cells with paranuclear rhabdoid inclusions, a mesenchymal and epithelial immunohistochemical profile, and 22q deletions with inactivation of the INI1/hSNF5 gene. Although they usually occur in young children, AT/RTs are being recognized in adults with increasing frequency. We report the cytologic features of an AT/RT from the cerebellum of a 45-year-old man and discuss the differential diagnosis in adults.

Original languageEnglish (US)
Pages (from-to)60-63
Number of pages4
JournalDiagnostic cytopathology
Volume31
Issue number1
DOIs
StatePublished - Jul 1 2004

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Keywords

  • Brain
  • Cytology
  • Rhabdoid
  • Tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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