Au-Catalyzed Pentannulation Reaction of Propargylic Esters Occurring at C(sp3)-H Site

Kazem Roohollah Shiroodi, Masumi Sugawara, Maxim Ratushnyy, Douglas C. Yarbrough, Donald J. Wink, Vladimir Gevorgyan

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


A gold-catalyzed cascade cyclization reaction of easily accessible propargylic esters to cyclopentenones has been developed. This transformation features an unprecedented pentannulation reaction of propargylic esters which occurs at an unactivated C(sp3)-H site to efficiently produce functionalized mono-, bis-, and tricyclic cyclopentenones.

Original languageEnglish (US)
Pages (from-to)4062-4065
Number of pages4
JournalOrganic Letters
Issue number16
StatePublished - Aug 7 2015
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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