A gold-catalyzed cascade cyclization reaction of easily accessible propargylic esters to cyclopentenones has been developed. This transformation features an unprecedented pentannulation reaction of propargylic esters which occurs at an unactivated C(sp3)-H site to efficiently produce functionalized mono-, bis-, and tricyclic cyclopentenones.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry