Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Jiyeon Kim; Zeping Hu; Ling Cai; Kailong Li; Eunhee Choi; Brandon Faubert; Divya Bezwada; Jaime Rodriguez-Canales; Pamela Villalobos; Yu Fen Lin; Min Ni; Kenneth E. Huffman; Luc Girard; Lauren A. Byers; Keziban Unsal-Kacmaz; Christopher G. Peña; John V. Heymach; Els Wauters; Johan Vansteenkiste; Diego H. Castrillon; Benjamin P.C. Chen; Ignacio Wistuba; Diether Lambrechts; Jian Xu; John D. Minna; Ralph J. DeBerardinis

doi:10.1038/s41586-019-1133-3

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Jiyeon Kim, Zeping Hu, Ling Cai, Kailong Li, Eunhee Choi, Brandon Faubert, Divya Bezwada, Jaime Rodriguez-Canales, Pamela Villalobos, Yu Fen Lin, Min Ni, Kenneth E. Huffman, Luc Girard, Lauren A. Byers, Keziban Unsal-Kacmaz, Christopher G. Peña, John V. Heymach, Els Wauters, Johan Vansteenkiste, Diego H. CastrillonBenjamin P.C. Chen, Ignacio Wistuba, Diether Lambrechts, Jian Xu, John D. Minna, Ralph J. DeBerardinis

Research output: Contribution to journal › Comment/debate › peer-review

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Abstract

Further analysis has revealed that the signal reported in Extended Data Fig. 1c of this Letter is attributed to phosphorylethanolamine, not carbamoyl phosphate. A newly developed derivatization method revealed that the level of carbamoyl phosphate in these NSCLC extracts is below the detection threshold of approximately 10 nanomoles. These findings do not alter the overall conclusions of the Letter; see associated Amendment for full details. The Letter has not been corrected online.

Original language	English (US)
Pages (from-to)	E4
Journal	Nature
Volume	569
Issue number	7756
DOIs	https://doi.org/10.1038/s41586-019-1133-3
State	Published - May 16 2019

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Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., ... DeBerardinis, R. J. (2019). Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359). Nature, 569(7756), E4. https://doi.org/10.1038/s41586-019-1133-3

Kim, J, Hu, Z , Cai, L, Li, K, Choi, E, Faubert, B, Bezwada, D, Rodriguez-Canales, J, Villalobos, P, Lin, YF, Ni, M, Huffman, KE, Girard, L, Byers, LA, Unsal-Kacmaz, K, Peña, CG, Heymach, JV, Wauters, E, Vansteenkiste, J, Castrillon, DH, Chen, BPC, Wistuba, I, Lambrechts, D, Xu, J, Minna, JD & DeBerardinis, RJ 2019, 'Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)', Nature, vol. 569, no. 7756, pp. E4. https://doi.org/10.1038/s41586-019-1133-3

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title = "Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)",

abstract = "Further analysis has revealed that the signal reported in Extended Data Fig. 1c of this Letter is attributed to phosphorylethanolamine, not carbamoyl phosphate. A newly developed derivatization method revealed that the level of carbamoyl phosphate in these NSCLC extracts is below the detection threshold of approximately 10 nanomoles. These findings do not alter the overall conclusions of the Letter; see associated Amendment for full details. The Letter has not been corrected online.",

author = "Jiyeon Kim and Zeping Hu and Ling Cai and Kailong Li and Eunhee Choi and Brandon Faubert and Divya Bezwada and Jaime Rodriguez-Canales and Pamela Villalobos and Lin, {Yu Fen} and Min Ni and Huffman, {Kenneth E.} and Luc Girard and Byers, {Lauren A.} and Keziban Unsal-Kacmaz and Pe{\~n}a, {Christopher G.} and Heymach, {John V.} and Els Wauters and Johan Vansteenkiste and Castrillon, {Diego H.} and Chen, {Benjamin P.C.} and Ignacio Wistuba and Diether Lambrechts and Jian Xu and Minna, {John D.} and DeBerardinis, {Ralph J.}",

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T2 - CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

AU - Kim, Jiyeon

AU - Hu, Zeping

AU - Cai, Ling

AU - Li, Kailong

AU - Choi, Eunhee

AU - Faubert, Brandon

AU - Bezwada, Divya

AU - Rodriguez-Canales, Jaime

AU - Villalobos, Pamela

AU - Lin, Yu Fen

AU - Ni, Min

AU - Huffman, Kenneth E.

AU - Girard, Luc

AU - Byers, Lauren A.

AU - Unsal-Kacmaz, Keziban

AU - Peña, Christopher G.

AU - Heymach, John V.

AU - Wauters, Els

AU - Vansteenkiste, Johan

AU - Castrillon, Diego H.

AU - Chen, Benjamin P.C.

AU - Wistuba, Ignacio

AU - Lambrechts, Diether

AU - Xu, Jian

AU - Minna, John D.

AU - DeBerardinis, Ralph J.

PY - 2019/5/16

Y1 - 2019/5/16

N2 - Further analysis has revealed that the signal reported in Extended Data Fig. 1c of this Letter is attributed to phosphorylethanolamine, not carbamoyl phosphate. A newly developed derivatization method revealed that the level of carbamoyl phosphate in these NSCLC extracts is below the detection threshold of approximately 10 nanomoles. These findings do not alter the overall conclusions of the Letter; see associated Amendment for full details. The Letter has not been corrected online.

AB - Further analysis has revealed that the signal reported in Extended Data Fig. 1c of this Letter is attributed to phosphorylethanolamine, not carbamoyl phosphate. A newly developed derivatization method revealed that the level of carbamoyl phosphate in these NSCLC extracts is below the detection threshold of approximately 10 nanomoles. These findings do not alter the overall conclusions of the Letter; see associated Amendment for full details. The Letter has not been corrected online.

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Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Abstract

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