Autism and cerebellar dysfunction: Evidence from animal models

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Autism is a prevalent neurodevelopmental disorder whose origins are not well understood. Cerebellar involvement has been implicated in the pathogenesis of autism spectrum disorders with increasing evidence from both clinical studies and animal models supporting an important role for cerebellar dysfunction in autism spectrum disorders. This article discusses the various cerebellar contributions to autism spectrum disorders. Both clinical and preclinical studies are discussed and future research directions highlighted.

Original languageEnglish (US)
JournalSeminars in Fetal and Neonatal Medicine
DOIs
Publication statusAccepted/In press - 2016

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Keywords

  • Animal models
  • Autism spectrum disorders
  • Cerebellum
  • Circuitry
  • Critical periods

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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