Automated quantification and analysis of facial asymmetry in children with arthritis in the temporomandibular joint

Tron A. Darvann, Nuno V. Hermann, Sune Demant, Per Larsen, Hildur Ólafsdóttir, Signe S. Thorup, Marek Zak, Angelo B. Lipira, Alex A. Kane, Daniel Govier, Helena Schatz, Daniel Rueckert, Sven Kreiborg

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

We present an automated method of spatially detailed 3D asymmetry quantification of face surfaces obtained in a stereophotogrammetric system, and the method was applied to a population of children with juvenile idiopathic arthritis (JIA) who have involvement of one temporomandibular joint (TMJ). Non-rigid registration of a patient face surface to a mirrored version of the same face surface provided a spatially dense map of left-right point correspondences that were used in the asymmetry calculation. For inter-patient comparison and modeling, detailed point correspondence was obtained by non-rigid registration of a symmetric atlas surface to a symmetric version of the patient surface. The method was validated by comparison to a landmark based method of asymmetry quantification, and the two methods were seen to provide similar results. The method was seen to be able to quantify typical patterns of asymmetry in JIA subjects with affected TMJ and compare them to a control population.

Original languageEnglish (US)
Title of host publication2011 8th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI'11
Pages1193-1196
Number of pages4
DOIs
StatePublished - 2011
Event2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11 - Chicago, IL, United States
Duration: Mar 30 2011Apr 2 2011

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11
CountryUnited States
CityChicago, IL
Period3/30/114/2/11

Keywords

  • Asymmetry
  • atlas-based methods
  • craniofacial malformations
  • juvenile idiopathic arthritis
  • non-rigid registration
  • temporomandibular joint

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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