Autophagy Keeps the Balance in Tissue Homeostasis

Research output: Contribution to journalShort survey

2 Scopus citations

Abstract

Gut cells are exposed to diverse insults that necessitate their replacement from a stem cell pool balancing differentiation and proliferation. In this issue of Developmental Cell, Zhang and colleagues (2019) show autophagy-mediated regulation of EGFR signaling cell autonomously controls intestinal stem cell proliferation, with implications for human colorectal cancer development.

Original languageEnglish (US)
Pages (from-to)499-500
Number of pages2
JournalDevelopmental cell
Volume49
Issue number4
DOIs
StatePublished - May 20 2019

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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