Autophagy Keeps the Balance in Tissue Homeostasis

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Abstract

Gut cells are exposed to diverse insults that necessitate their replacement from a stem cell pool balancing differentiation and proliferation. In this issue of Developmental Cell, Zhang and colleagues (2019) show autophagy-mediated regulation of EGFR signaling cell autonomously controls intestinal stem cell proliferation, with implications for human colorectal cancer development.

Original languageEnglish (US)
Pages (from-to)499-500
Number of pages2
JournalDevelopmental Cell
Volume49
Issue number4
DOIs
StatePublished - May 20 2019

Fingerprint

Tissue homeostasis
Autophagy
Stem cells
Homeostasis
Cell signaling
Cell proliferation
Stem Cells
Colorectal Neoplasms
Cell Proliferation

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

Cite this

Autophagy Keeps the Balance in Tissue Homeostasis. / Buszczak, Michael; Kramer, Helmut.

In: Developmental Cell, Vol. 49, No. 4, 20.05.2019, p. 499-500.

Research output: Contribution to journalShort survey

@article{dbf66c1bc63d42cdbc46884dee83f9d5,
title = "Autophagy Keeps the Balance in Tissue Homeostasis",
abstract = "Gut cells are exposed to diverse insults that necessitate their replacement from a stem cell pool balancing differentiation and proliferation. In this issue of Developmental Cell, Zhang and colleagues (2019) show autophagy-mediated regulation of EGFR signaling cell autonomously controls intestinal stem cell proliferation, with implications for human colorectal cancer development.",
author = "Michael Buszczak and Helmut Kramer",
year = "2019",
month = "5",
day = "20",
doi = "10.1016/j.devcel.2019.05.005",
language = "English (US)",
volume = "49",
pages = "499--500",
journal = "Developmental Cell",
issn = "1534-5807",
publisher = "Cell Press",
number = "4",

}

TY - JOUR

T1 - Autophagy Keeps the Balance in Tissue Homeostasis

AU - Buszczak, Michael

AU - Kramer, Helmut

PY - 2019/5/20

Y1 - 2019/5/20

N2 - Gut cells are exposed to diverse insults that necessitate their replacement from a stem cell pool balancing differentiation and proliferation. In this issue of Developmental Cell, Zhang and colleagues (2019) show autophagy-mediated regulation of EGFR signaling cell autonomously controls intestinal stem cell proliferation, with implications for human colorectal cancer development.

AB - Gut cells are exposed to diverse insults that necessitate their replacement from a stem cell pool balancing differentiation and proliferation. In this issue of Developmental Cell, Zhang and colleagues (2019) show autophagy-mediated regulation of EGFR signaling cell autonomously controls intestinal stem cell proliferation, with implications for human colorectal cancer development.

UR - http://www.scopus.com/inward/record.url?scp=85065252998&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85065252998&partnerID=8YFLogxK

U2 - 10.1016/j.devcel.2019.05.005

DO - 10.1016/j.devcel.2019.05.005

M3 - Short survey

C2 - 31112694

AN - SCOPUS:85065252998

VL - 49

SP - 499

EP - 500

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 4

ER -