Abstract
Femoral facial syndrome (FFS) is comprised of cleft palate, mierognathia, short or absent femora, and vertebral and genitourinary malformations. We report on a stillborn fetus with FFS delivered to a mother with gestational diabetes. Prenatal ultrasound examination showed abnormalities at 21 weeks of gestation; prior ultrasound findings were interpreted as normal. Long bone histology showed disorganization of the growth plate with a relative decrease in cartilaginous matrix and vacuolization and binucleation of the chondrocytes.
Original language | English (US) |
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Pages (from-to) | 76-79 |
Number of pages | 4 |
Journal | American Journal of Medical Genetics |
Volume | 71 |
Issue number | 1 |
State | Published - 1997 |
Keywords
- Autopsy
- Femoral facial syndrome
- Femoral hypoplasia-unusual faciès syndrome
- Histology
- Radiographs
- Ultrasound
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)