B-cell tolerance. IV. Differential role of surface IgM and IgD in determining tolerance susceptibility of murine B cells

E. S. Vitetta, J. C. Cambier, F. S. Ligler, J. R. Kettman, J. W. Uhr

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Abstract

They have removed surface IgM or IgD by antibody-induced capping and assessed the tolerance susceptibility of the treated cells. The results demonstrate that removal of IgD, but not IgM, from TD responders increases their susceptibility to tolerance induction.

Original languageEnglish (US)
Pages (from-to)1804-1808
Number of pages5
JournalJournal of Experimental Medicine
Volume146
Issue number6
StatePublished - 1977

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Immunoglobulin D
Immunoglobulin M
B-Lymphocytes
Antibodies

ASJC Scopus subject areas

  • Immunology

Cite this

B-cell tolerance. IV. Differential role of surface IgM and IgD in determining tolerance susceptibility of murine B cells. / Vitetta, E. S.; Cambier, J. C.; Ligler, F. S.; Kettman, J. R.; Uhr, J. W.

In: Journal of Experimental Medicine, Vol. 146, No. 6, 1977, p. 1804-1808.

Research output: Contribution to journalArticle

Vitetta, E. S. ; Cambier, J. C. ; Ligler, F. S. ; Kettman, J. R. ; Uhr, J. W. / B-cell tolerance. IV. Differential role of surface IgM and IgD in determining tolerance susceptibility of murine B cells. In: Journal of Experimental Medicine. 1977 ; Vol. 146, No. 6. pp. 1804-1808.
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AU - Uhr, J. W.

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