Abstract
We have introduced general ways in which B cells play a role in protective immunity against microbes. Although B cells were originally defined solely as antibody-producing cells, it is now known that they have other functions that are equally as important as producing antibodies. These include antigen-presenting cell activity and the production of natural IgM antibodies that trigger complement activation. Future research will undoubtedly help define how changes in B-cell functions following injury and sepsis affect the development of effective or suppressive immunity in patients who are predisposed to sepsis, are undergoing sepsis, or are in septic shock.
| Original language | English (US) |
|---|---|
| Pages (from-to) | S514-S516 |
| Journal | Critical care medicine |
| Volume | 33 |
| Issue number | 12 SUPPL. |
| DOIs | |
| State | Published - Dec 2005 |
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine
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MacConmara, M., & Lederer, J. A. (2005). B cells. Critical care medicine, 33(12 SUPPL.), S514-S516. https://doi.org/10.1097/01.CCM.0000190616.15952.4B