Backstimulation by Blastogenic Factor in the Primed LD Typing Test: Possible Role in Anomalous Responses

J. Gordon, M. Uotila, H. Rode

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The anomalous false‐positive results often found in the primed lymphocyte typing (PLT) test seem to be partially due to the release of blastogenic factor (BF) from the stimulating cell, resulting in back stimulation of the primed lymphocyte. These anomalous responses can be greatly reduced by treating the stimulator cell with high doses of irradiation or with puromycin.

Original languageEnglish (US)
Pages (from-to)327-333
Number of pages7
JournalTissue Antigens
Volume13
Issue number5
DOIs
StatePublished - May 1979

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Biochemistry
  • Genetics

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