Bacteria as Specific Binding Agents for an Isotopic Assay of Serum Folate

M. S. McCall, J. D. White, E. P. Frenkel

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Saturation analysis or competitive inhibition utilizing bacteria (L. casei) as the specific binder permitted the measurement of serum folate. Unlike conventional microbiologic techniques, organism growth rate was not determined. This new “radiomicrobiologic” approach quantitated serum folate by competitive binding of tritiated folic acid during the early “lag” phase of bacterial growth.

Original languageEnglish (US)
Pages (from-to)536-538
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume134
Issue number2
DOIs
StatePublished - Jun 1970

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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