Saturation analysis or competitive inhibition utilizing bacteria (L. casei) as the specific binder permitted the measurement of serum folate. Unlike conventional microbiologic techniques, organism growth rate was not determined. This new “radiomicrobiologic” approach quantitated serum folate by competitive binding of tritiated folic acid during the early “lag” phase of bacterial growth.
|Original language||English (US)|
|Number of pages||3|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Jun 1970|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)