Bacterial meningitis from Rothia mucilaginosa in patients with malignancy or undergoing hematopoietic stem cell transplantation

Alisa B. Lee Md, Paul Harker-Murray, Patricia Ferrieri, Mark R. Schleiss, Jakub Tolar

Research output: Contribution to journalArticle

18 Scopus citations


Opportunistic infections contribute to morbidity and mortality of patients undergoing hematopoietic stem cell transplantation and treatment for malignancies. Rothia mucilaginosa, a gram-positive bacterium, is responsible for rare, but often fatal meningitis in severely immunocompromised patients. We describe two cases of meningitis from discrete strains of R. mucilaginosa on our pediatric bone marrow transplant unit, summarize the published cases of R. mucilaginosa meningitis in oncology and stem cell transplant patients, and provide updated recommendations regarding the use of antibiotic therapy in this patient population.

Original languageEnglish (US)
Pages (from-to)673-676
Number of pages4
JournalPediatric Blood and Cancer
Issue number3
Publication statusPublished - Mar 2008



  • Bone marrow
  • Intrathecal
  • Intraventricular
  • Micrococcus
  • Oncology

ASJC Scopus subject areas

  • Cancer Research
  • Pediatrics, Perinatology, and Child Health
  • Hematology

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