TY - JOUR
T1 - Bacterial reductionism
T2 - Host thiols enhance virulence
AU - Sperandio, Vanessa
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015
Y1 - 2015
N2 - Intracellular bacteria exploit host cytosolic signals to upregulate virulence genes. In this issue of Cell Host and Microbe, Wong et al. (2015) show that Burkholderia pseudomallei senses host cytosolic glutathione, a low-molecular-weight thiol, through the membrane-bound histidine sensor kinase VirA, highlighting the importance of inter-kingdom signaling in bacterial pathogenesis.
AB - Intracellular bacteria exploit host cytosolic signals to upregulate virulence genes. In this issue of Cell Host and Microbe, Wong et al. (2015) show that Burkholderia pseudomallei senses host cytosolic glutathione, a low-molecular-weight thiol, through the membrane-bound histidine sensor kinase VirA, highlighting the importance of inter-kingdom signaling in bacterial pathogenesis.
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UR - http://www.scopus.com/inward/citedby.url?scp=84943163854&partnerID=8YFLogxK
U2 - 10.1016/j.chom.2015.06.010
DO - 10.1016/j.chom.2015.06.010
M3 - Short survey
C2 - 26159714
AN - SCOPUS:84943163854
SN - 1931-3128
VL - 18
SP - 7
EP - 8
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 1
ER -