Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting

Melissa R. Ham; Pamela Okada; Perrin C. White

doi:10.1111/j.1399-543X.2004.00032.x

Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting

Melissa R. Ham, Pamela Okada, Perrin C. White

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Objective: Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus marked by characteristic biochemical derangements. Diagnosis and management involve frequent evaluation of these biochemical parameters. Reliable bedside equivalents for these laboratory studies may help reduce the time to treatment and reduce costs. Methods: We evaluated the precision and bias of a bedside serum ketone meter in the acute care setting. Serum ketone results using the Precision Xtra™ glucometer/ketone meter (Abbott Laboratories, MediSense Products Inc., Bedford, MA, USA) correlated strongly with the Children's Medical Center of Dallas' laboratory values within the meter's value range. Results: Meter ketone values steadily decreased during the treatment of DKA as pH and CO₂ levels increased and acidosis resolved. Conclusion: Therefore, the meter may be useful in monitoring therapy for DKA. This meter may also prove useful in identifying patients at risk for DKA in physicians' offices or at home.

Original language	English (US)
Pages (from-to)	39-43
Number of pages	5
Journal	Pediatric Diabetes
Volume	5
Issue number	1
DOIs	https://doi.org/10.1111/j.1399-543X.2004.00032.x
State	Published - Mar 2004

Keywords

Ketoacidosis
Ketone meter
Type 1 diabetes mellitus
β-hydroxybutyrate

ASJC Scopus subject areas

Internal Medicine
Pediatrics, Perinatology, and Child Health
Endocrinology, Diabetes and Metabolism

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10.1111/j.1399-543X.2004.00032.x

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title = "Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting",

abstract = "Objective: Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus marked by characteristic biochemical derangements. Diagnosis and management involve frequent evaluation of these biochemical parameters. Reliable bedside equivalents for these laboratory studies may help reduce the time to treatment and reduce costs. Methods: We evaluated the precision and bias of a bedside serum ketone meter in the acute care setting. Serum ketone results using the Precision Xtra{\texttrademark} glucometer/ketone meter (Abbott Laboratories, MediSense Products Inc., Bedford, MA, USA) correlated strongly with the Children's Medical Center of Dallas' laboratory values within the meter's value range. Results: Meter ketone values steadily decreased during the treatment of DKA as pH and CO2 levels increased and acidosis resolved. Conclusion: Therefore, the meter may be useful in monitoring therapy for DKA. This meter may also prove useful in identifying patients at risk for DKA in physicians' offices or at home.",

keywords = "Ketoacidosis, Ketone meter, Type 1 diabetes mellitus, β-hydroxybutyrate",

author = "Ham, {Melissa R.} and Pamela Okada and White, {Perrin C.}",

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doi = "10.1111/j.1399-543X.2004.00032.x",

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T1 - Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting

AU - Ham, Melissa R.

AU - Okada, Pamela

AU - White, Perrin C.

PY - 2004/3

Y1 - 2004/3

N2 - Objective: Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus marked by characteristic biochemical derangements. Diagnosis and management involve frequent evaluation of these biochemical parameters. Reliable bedside equivalents for these laboratory studies may help reduce the time to treatment and reduce costs. Methods: We evaluated the precision and bias of a bedside serum ketone meter in the acute care setting. Serum ketone results using the Precision Xtra™ glucometer/ketone meter (Abbott Laboratories, MediSense Products Inc., Bedford, MA, USA) correlated strongly with the Children's Medical Center of Dallas' laboratory values within the meter's value range. Results: Meter ketone values steadily decreased during the treatment of DKA as pH and CO2 levels increased and acidosis resolved. Conclusion: Therefore, the meter may be useful in monitoring therapy for DKA. This meter may also prove useful in identifying patients at risk for DKA in physicians' offices or at home.

AB - Objective: Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus marked by characteristic biochemical derangements. Diagnosis and management involve frequent evaluation of these biochemical parameters. Reliable bedside equivalents for these laboratory studies may help reduce the time to treatment and reduce costs. Methods: We evaluated the precision and bias of a bedside serum ketone meter in the acute care setting. Serum ketone results using the Precision Xtra™ glucometer/ketone meter (Abbott Laboratories, MediSense Products Inc., Bedford, MA, USA) correlated strongly with the Children's Medical Center of Dallas' laboratory values within the meter's value range. Results: Meter ketone values steadily decreased during the treatment of DKA as pH and CO2 levels increased and acidosis resolved. Conclusion: Therefore, the meter may be useful in monitoring therapy for DKA. This meter may also prove useful in identifying patients at risk for DKA in physicians' offices or at home.

KW - Ketoacidosis

KW - Ketone meter

KW - Type 1 diabetes mellitus

KW - β-hydroxybutyrate

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Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting

Abstract

Keywords

ASJC Scopus subject areas

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