Benign pairs: A useful discriminating feature in fine needle aspirates of the breast

Gordon H. Yu, Seema Sethi, Ricardo S. Cajulis, Sefik T. Gokaslan, Denise Frias-Hidvegi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

OBJECTIVE: To determine the diagnostic utility of the finding of naked, bipolar nuclei in fine needle aspirates of breast lesions. STUDY DESIGN: Aspirate smears from 150 cases of histologically proven benign (77) and malignant (73) breast lesions were evaluated for the presence of stripped, bipolar nuclei in the smear background as singlets as well as closely associated pairs. RESULTS: The presence of such pairs was a more specific indicator of benign entities (present in 70% of benign lesions vs. 1% of carcinomas) when compared to single, bare nuclei alone (present in 94% of benign lesions vs. 45% of carcinomas). Large numbers of such 'benign pairs' also strongly favored the diagnosis of fibroadenoma within the benign subgroup. CONCLUSION: The presence of bipolar nuclear pairs is a valuable addition to the finding of singlets in the diagnosis of benign breast lesions and their subclassification.

Original languageEnglish (US)
Pages (from-to)721-726
Number of pages6
JournalActa Cytologica
Volume41
Issue number3
StatePublished - 1997

Fingerprint

Needles
Breast
Carcinoma
Fibroadenoma

Keywords

  • aspiration biopsy
  • benign pairs
  • breast neoplasms
  • fibroadenoma

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology

Cite this

Yu, G. H., Sethi, S., Cajulis, R. S., Gokaslan, S. T., & Frias-Hidvegi, D. (1997). Benign pairs: A useful discriminating feature in fine needle aspirates of the breast. Acta Cytologica, 41(3), 721-726.

Benign pairs : A useful discriminating feature in fine needle aspirates of the breast. / Yu, Gordon H.; Sethi, Seema; Cajulis, Ricardo S.; Gokaslan, Sefik T.; Frias-Hidvegi, Denise.

In: Acta Cytologica, Vol. 41, No. 3, 1997, p. 721-726.

Research output: Contribution to journalArticle

Yu, GH, Sethi, S, Cajulis, RS, Gokaslan, ST & Frias-Hidvegi, D 1997, 'Benign pairs: A useful discriminating feature in fine needle aspirates of the breast', Acta Cytologica, vol. 41, no. 3, pp. 721-726.
Yu GH, Sethi S, Cajulis RS, Gokaslan ST, Frias-Hidvegi D. Benign pairs: A useful discriminating feature in fine needle aspirates of the breast. Acta Cytologica. 1997;41(3):721-726.
Yu, Gordon H. ; Sethi, Seema ; Cajulis, Ricardo S. ; Gokaslan, Sefik T. ; Frias-Hidvegi, Denise. / Benign pairs : A useful discriminating feature in fine needle aspirates of the breast. In: Acta Cytologica. 1997 ; Vol. 41, No. 3. pp. 721-726.
@article{fc4a1bb59def4a8fae4011af48248cf4,
title = "Benign pairs: A useful discriminating feature in fine needle aspirates of the breast",
abstract = "OBJECTIVE: To determine the diagnostic utility of the finding of naked, bipolar nuclei in fine needle aspirates of breast lesions. STUDY DESIGN: Aspirate smears from 150 cases of histologically proven benign (77) and malignant (73) breast lesions were evaluated for the presence of stripped, bipolar nuclei in the smear background as singlets as well as closely associated pairs. RESULTS: The presence of such pairs was a more specific indicator of benign entities (present in 70{\%} of benign lesions vs. 1{\%} of carcinomas) when compared to single, bare nuclei alone (present in 94{\%} of benign lesions vs. 45{\%} of carcinomas). Large numbers of such 'benign pairs' also strongly favored the diagnosis of fibroadenoma within the benign subgroup. CONCLUSION: The presence of bipolar nuclear pairs is a valuable addition to the finding of singlets in the diagnosis of benign breast lesions and their subclassification.",
keywords = "aspiration biopsy, benign pairs, breast neoplasms, fibroadenoma",
author = "Yu, {Gordon H.} and Seema Sethi and Cajulis, {Ricardo S.} and Gokaslan, {Sefik T.} and Denise Frias-Hidvegi",
year = "1997",
language = "English (US)",
volume = "41",
pages = "721--726",
journal = "Acta Cytologica",
issn = "0001-5547",
publisher = "Science Printers and Publishers Inc.",
number = "3",

}

TY - JOUR

T1 - Benign pairs

T2 - A useful discriminating feature in fine needle aspirates of the breast

AU - Yu, Gordon H.

AU - Sethi, Seema

AU - Cajulis, Ricardo S.

AU - Gokaslan, Sefik T.

AU - Frias-Hidvegi, Denise

PY - 1997

Y1 - 1997

N2 - OBJECTIVE: To determine the diagnostic utility of the finding of naked, bipolar nuclei in fine needle aspirates of breast lesions. STUDY DESIGN: Aspirate smears from 150 cases of histologically proven benign (77) and malignant (73) breast lesions were evaluated for the presence of stripped, bipolar nuclei in the smear background as singlets as well as closely associated pairs. RESULTS: The presence of such pairs was a more specific indicator of benign entities (present in 70% of benign lesions vs. 1% of carcinomas) when compared to single, bare nuclei alone (present in 94% of benign lesions vs. 45% of carcinomas). Large numbers of such 'benign pairs' also strongly favored the diagnosis of fibroadenoma within the benign subgroup. CONCLUSION: The presence of bipolar nuclear pairs is a valuable addition to the finding of singlets in the diagnosis of benign breast lesions and their subclassification.

AB - OBJECTIVE: To determine the diagnostic utility of the finding of naked, bipolar nuclei in fine needle aspirates of breast lesions. STUDY DESIGN: Aspirate smears from 150 cases of histologically proven benign (77) and malignant (73) breast lesions were evaluated for the presence of stripped, bipolar nuclei in the smear background as singlets as well as closely associated pairs. RESULTS: The presence of such pairs was a more specific indicator of benign entities (present in 70% of benign lesions vs. 1% of carcinomas) when compared to single, bare nuclei alone (present in 94% of benign lesions vs. 45% of carcinomas). Large numbers of such 'benign pairs' also strongly favored the diagnosis of fibroadenoma within the benign subgroup. CONCLUSION: The presence of bipolar nuclear pairs is a valuable addition to the finding of singlets in the diagnosis of benign breast lesions and their subclassification.

KW - aspiration biopsy

KW - benign pairs

KW - breast neoplasms

KW - fibroadenoma

UR - http://www.scopus.com/inward/record.url?scp=0030993146&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030993146&partnerID=8YFLogxK

M3 - Article

C2 - 9167691

AN - SCOPUS:0030993146

VL - 41

SP - 721

EP - 726

JO - Acta Cytologica

JF - Acta Cytologica

SN - 0001-5547

IS - 3

ER -