BETs abet Tam-R in ER-positive breast cancer

Prasanna G. Alluri, Irfan A. Asangani, Arul M. Chinnaiyan

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Epigenetic modifications such as histone acetylation play a central role in the transcriptional regulation of many oncogenic drivers. Accumulating evidence suggests that pharmacological modulation of certain key epigenetic reader proteins such as BRD2/3/4 may serve as an attractive strategy for treatment of many cancers, including tamoxifen-resistant breast cancer.

Original languageEnglish (US)
Pages (from-to)899-900
Number of pages2
JournalCell Research
Volume24
Issue number8
DOIs
StatePublished - Aug 2014

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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