Abstract
Epigenetic modifications such as histone acetylation play a central role in the transcriptional regulation of many oncogenic drivers. Accumulating evidence suggests that pharmacological modulation of certain key epigenetic reader proteins such as BRD2/3/4 may serve as an attractive strategy for treatment of many cancers, including tamoxifen-resistant breast cancer.
Original language | English (US) |
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Pages (from-to) | 899-900 |
Number of pages | 2 |
Journal | Cell Research |
Volume | 24 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2014 |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology