Beyond the limits: Palladium-N-heterocyclic carbene-based catalytic system enables highly efficient [4+2] benzannulation reactions

Olga V. Zatolochnaya; Alexey V. Galenko; Vladimir Gevorgyan

doi:10.1002/adsc.201100983

Beyond the limits: Palladium-N-heterocyclic carbene-based catalytic system enables highly efficient [4+2] benzannulation reactions

Olga V. Zatolochnaya, Alexey V. Galenko, Vladimir Gevorgyan

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A highly efficient catalytic system for the palladium-catalyzed [4+2] benzannulation reaction of enynes and enynophiles has been developed. The use of an N-heterocyclic carbene-based palladium precursor allowed us to achieve turnover numbers up to 1800. The new catalytic system has enabled an expansion of the scope of the [4+2] homo-benzannulation reaction.

Original language	English (US)
Pages (from-to)	1149-1155
Number of pages	7
Journal	Advanced Synthesis and Catalysis
Volume	354
Issue number	6
DOIs	https://doi.org/10.1002/adsc.201100983
State	Published - Apr 16 2012
Externally published	Yes

Keywords

N-heterocyclic carbenes
benzannulation
cycloaddition
palladium catalysis
turnover number

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1002/adsc.201100983

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AU - Gevorgyan, Vladimir

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Beyond the limits: Palladium-N-heterocyclic carbene-based catalytic system enables highly efficient [4+2] benzannulation reactions

Abstract

Keywords

ASJC Scopus subject areas

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