Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

Medicine & Life Sciences

• Mechanistic Target of Rapamycin Complex 1 100%
• Lipogenesis 97%
• Gluconeogenesis 96%
• Psychological Inhibition 64%
• Insulin 54%
• Liver 41%
• Sterol Regulatory Element Binding Protein 1 39%
• Ribosomal Protein S6 Kinases 20%
• Insulin Resistance 17%
• Messenger RNA 16%
• Sirolimus 15%
• Phosphotransferases 11%
• Aptitude 9%
• Phosphatidylinositol 3-Kinases 7%
• Fatty Acids 6%
• Hepatocytes 6%
• Rodentia 5%
• Genes 5%
• Fasting 5%
• Transcription Factors 5%
• Glucose 4%