Abstract
Purpose: To describe a case of bilateral keratoconjunctivitis in a patient with lichen planus. Methods: Case report and review of the English literature. Results: To our knowledge, this is the fourth reported case of keratoconjunctivitis associated with lichen planus. A 33-year-old Navajo man with lichen planus had recurrent and progressive keratoconjunctivitis that failed to improve on multiple topical medications. Tapered oral prednisone, 2% topical cyclosporin, and amniotic membrane transplantation pacified the acute exacerbation. Conclusions: Our patient with lichen planus developed an ocular surface disease with cicatricial conjunctivitis, keratouveitis, keratoconjunctivitis sicca, punctate epithelial erosions, and persistent epithelial defects leading to noninfectious or infectious corneal ulceration. Amniotic membrane transplantation may play an adjunctive role in refractory cases of lichen planus-related keratoconjunctivitis. Topical cyclosporin may stabilize the ocular surface when combined with systemic immunosuppression in severe cases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 100-105 |
| Number of pages | 6 |
| Journal | Cornea |
| Volume | 23 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2004 |
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Keywords
- Amniotic membrane
- Cicatricial conjunctivitis
- Cyclosporin
- Keratitis
- Lichen planus
ASJC Scopus subject areas
- Ophthalmology
Cite this
Bilateral Keratoconjunctivitis Associated with Lichen Planus. / Rhee, Michelle K.; Mootha, Venkateswara.
In: Cornea, Vol. 23, No. 1, 01.2004, p. 100-105.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bilateral Keratoconjunctivitis Associated with Lichen Planus
AU - Rhee, Michelle K.
AU - Mootha, Venkateswara
PY - 2004/1
Y1 - 2004/1
N2 - Purpose: To describe a case of bilateral keratoconjunctivitis in a patient with lichen planus. Methods: Case report and review of the English literature. Results: To our knowledge, this is the fourth reported case of keratoconjunctivitis associated with lichen planus. A 33-year-old Navajo man with lichen planus had recurrent and progressive keratoconjunctivitis that failed to improve on multiple topical medications. Tapered oral prednisone, 2% topical cyclosporin, and amniotic membrane transplantation pacified the acute exacerbation. Conclusions: Our patient with lichen planus developed an ocular surface disease with cicatricial conjunctivitis, keratouveitis, keratoconjunctivitis sicca, punctate epithelial erosions, and persistent epithelial defects leading to noninfectious or infectious corneal ulceration. Amniotic membrane transplantation may play an adjunctive role in refractory cases of lichen planus-related keratoconjunctivitis. Topical cyclosporin may stabilize the ocular surface when combined with systemic immunosuppression in severe cases.
AB - Purpose: To describe a case of bilateral keratoconjunctivitis in a patient with lichen planus. Methods: Case report and review of the English literature. Results: To our knowledge, this is the fourth reported case of keratoconjunctivitis associated with lichen planus. A 33-year-old Navajo man with lichen planus had recurrent and progressive keratoconjunctivitis that failed to improve on multiple topical medications. Tapered oral prednisone, 2% topical cyclosporin, and amniotic membrane transplantation pacified the acute exacerbation. Conclusions: Our patient with lichen planus developed an ocular surface disease with cicatricial conjunctivitis, keratouveitis, keratoconjunctivitis sicca, punctate epithelial erosions, and persistent epithelial defects leading to noninfectious or infectious corneal ulceration. Amniotic membrane transplantation may play an adjunctive role in refractory cases of lichen planus-related keratoconjunctivitis. Topical cyclosporin may stabilize the ocular surface when combined with systemic immunosuppression in severe cases.
KW - Amniotic membrane
KW - Cicatricial conjunctivitis
KW - Cyclosporin
KW - Keratitis
KW - Lichen planus
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UR - http://www.scopus.com/inward/citedby.url?scp=0348049456&partnerID=8YFLogxK
U2 - 10.1097/00003226-200401000-00019
DO - 10.1097/00003226-200401000-00019
M3 - Article
C2 - 14701968
AN - SCOPUS:0348049456
VL - 23
SP - 100
EP - 105
JO - Cornea
JF - Cornea
SN - 0277-3740
IS - 1
ER -