Bilateral responses of prefrontal and motor cortices to repetitive Transcranial Magnetic Stimulation as measured by functional Near Infrared Spectroscopy

Fenghua Tian, Frank Andrew Kozel, Sameer Dhamne, Shawn M. McClintock, Paul Croarkin, Kimberly Mapes, Mustafa M. Husain, Hanli Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Simultaneously acquiring cortical functional Near Infrared Spectroscopy (fNIRS) during repeated Transcranial Magnetic Stimulation (rTMS) offers the possibility of directly investigating the effects of rTMS on brain regions without quantifiable behavioral changes. In this study, the left motor cortex and subsequently the left prefrontal cortex were stimulated at 1 Hz while fNIRS data was simultaneously acquired. Changes in hemodynamic signals were measured on both ipsilateral and contralateral sides. In each cortex, a significantly larger decrease in the concentration of oxygenated hemoglobin and a smaller increase in the concentration of deoxygenated hemoglobin during the stimulation periods were observed in both the motor and prefrontal cortices. The ipsilateral and contralateral changes showed high temporal consistency. Same experiment was repeated for each subject 2 or 3 days later. The hemodynamic responses associated with the stimulation showed good reproducibility in two sessions. To our knowledge, this is the first report of simultaneous fNIRS measurement of ipsilateral and contralateral changes of either the motor or prefrontal cortex during rTMS stimulation.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7161
DOIs
StatePublished - 2009
EventPhotonic Therapeutics and Diagnostics V - San Jose, CA, United States
Duration: Jan 24 2009Jan 26 2009

Other

OtherPhotonic Therapeutics and Diagnostics V
CountryUnited States
CitySan Jose, CA
Period1/24/091/26/09

Fingerprint

Near-infrared Spectroscopy
Near infrared spectroscopy
cortexes
Cortex
stimulation
Hemoglobin
infrared spectroscopy
Hemodynamics
Hemoglobins
hemoglobin
Brain
hemodynamic responses
Reproducibility
hemodynamics
brain
Experiments
Decrease
Experiment

Keywords

  • Functional Near Infrared Spectroscopy (fNIRS)
  • Hemoglobin
  • Motor cortex
  • Oxygenation
  • Prefrontal cortex
  • Repeated Transcranial Magnetic Stimulation (rTMS)

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Tian, F., Kozel, F. A., Dhamne, S., McClintock, S. M., Croarkin, P., Mapes, K., ... Liu, H. (2009). Bilateral responses of prefrontal and motor cortices to repetitive Transcranial Magnetic Stimulation as measured by functional Near Infrared Spectroscopy. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7161). [71613C] https://doi.org/10.1117/12.809343

Bilateral responses of prefrontal and motor cortices to repetitive Transcranial Magnetic Stimulation as measured by functional Near Infrared Spectroscopy. / Tian, Fenghua; Kozel, Frank Andrew; Dhamne, Sameer; McClintock, Shawn M.; Croarkin, Paul; Mapes, Kimberly; Husain, Mustafa M.; Liu, Hanli.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7161 2009. 71613C.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tian, F, Kozel, FA, Dhamne, S, McClintock, SM, Croarkin, P, Mapes, K, Husain, MM & Liu, H 2009, Bilateral responses of prefrontal and motor cortices to repetitive Transcranial Magnetic Stimulation as measured by functional Near Infrared Spectroscopy. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7161, 71613C, Photonic Therapeutics and Diagnostics V, San Jose, CA, United States, 1/24/09. https://doi.org/10.1117/12.809343
Tian F, Kozel FA, Dhamne S, McClintock SM, Croarkin P, Mapes K et al. Bilateral responses of prefrontal and motor cortices to repetitive Transcranial Magnetic Stimulation as measured by functional Near Infrared Spectroscopy. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7161. 2009. 71613C https://doi.org/10.1117/12.809343
Tian, Fenghua ; Kozel, Frank Andrew ; Dhamne, Sameer ; McClintock, Shawn M. ; Croarkin, Paul ; Mapes, Kimberly ; Husain, Mustafa M. ; Liu, Hanli. / Bilateral responses of prefrontal and motor cortices to repetitive Transcranial Magnetic Stimulation as measured by functional Near Infrared Spectroscopy. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7161 2009.
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