Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass

Lydia Ann Harris, Brandon D. Kayser, Consuelo Cefalo, Luca Marini, Jeramie D. Watrous, Jeffrey Ding, Mohit Jain, Jeffrey G. McDonald, Bonne M. Thompson, Elisa Fabbrini, J. Christopher Eagon, Bruce W. Patterson, Bettina Mittendorfer, Geltrude Mingrone, Samuel Klein

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Diabetes remission is greater after biliopancreatic diversion (BPD) than Roux-en-Y gastric bypass (RYGB) surgery. Harris and Kayser et al. report that in individuals matched for percentage weight loss after surgery, BPD induces the same improvement in β cell function but a greater improvement in insulin sensitivity than RYGB.

Original languageEnglish (US)
Pages (from-to)855-864.e3
JournalCell Metabolism
Volume30
Issue number5
DOIs
StatePublished - Nov 5 2019

Keywords

  • bariatric surgery
  • insulin sensitivity
  • obesity

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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    Harris, L. A., Kayser, B. D., Cefalo, C., Marini, L., Watrous, J. D., Ding, J., Jain, M., McDonald, J. G., Thompson, B. M., Fabbrini, E., Eagon, J. C., Patterson, B. W., Mittendorfer, B., Mingrone, G., & Klein, S. (2019). Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass. Cell Metabolism, 30(5), 855-864.e3. https://doi.org/10.1016/j.cmet.2019.09.002