Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17β-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells

Medicine & Life Sciences

• human HSD17B2 protein 100%
• Estrone 58%
• HEK293 Cells 50%
• NADP 50%
• 3 (or 17)-beta-hydroxysteroid dehydrogenase 41%
• Estradiol 40%
• NAD 9%
• Mutagenesis 9%
• Mutation 5%
• Oxidation-Reduction 4%
• Arginine 4%
• Phosphates 4%
• Estrogens 3%
• Steroids 3%
• Glucose 2%
• Proteins 1%