Biomechanical properties of grown cartilage are decreased in the presence of retinoic acid, chondroitinase ABC and ibuprofen

Chih Tung Chen, Peter A. Torzilli, Kenneth W. Fishbein, Richard G S Spencer, Walter E. Horton

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The biomechanical properties of cartilages grown in a hollow fiber bioreactor were discussed. Retinoic acid, chondroitinase ABC and ibuprofen were found to disrupt the formation of cartilage and decrease the biomechanical properties of the tissue. No significant differences in the biomechanical and biochemical properties of the cartilage segments were found from different locations along the BR.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
EditorsB.B. Lieber
Pages297-298
Number of pages2
Volume51
StatePublished - 2001
Event2001 ASME International Mechanical Engineering Congress and Exposition - New York, NY, United States
Duration: Nov 11 2001Nov 16 2001

Other

Other2001 ASME International Mechanical Engineering Congress and Exposition
CountryUnited States
CityNew York, NY
Period11/11/0111/16/01

ASJC Scopus subject areas

  • Engineering(all)

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    Chen, C. T., Torzilli, P. A., Fishbein, K. W., Spencer, R. G. S., & Horton, W. E. (2001). Biomechanical properties of grown cartilage are decreased in the presence of retinoic acid, chondroitinase ABC and ibuprofen. In B. B. Lieber (Ed.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 51, pp. 297-298)