Biopsy type does not influence sentinel lymph node status

Anees B. Chagpar, Charles R. Scoggins, Sunati Sahoo, Robert C. Martin, David J. Carlson, Alison L. Laidley, Souzan E. El-Eid, Terre Q. McGlothin, Robert D. Noyes, Phillip B. Ley, Todd M. Tuttle, Kelly M. McMasters

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Background: This study sought to determine whether the type of biopsy examination independently affects sentinel lymph node (SLN) status in breast cancer patients. Methods: A prospective multicenter study of patients who had SLN biopsy examination followed by axillary node dissection was analyzed to determine whether the type of biopsy examination influenced SLN status. Results: Of the 3853 patients studied, 32% had a positive SLN. Patients were diagnosed by fine-needle (N = 293), core-needle (N = 2154), excisional (N = 1386), or incisional (N = 20) biopsy procedures. The rates of SLN positivity for these groups were 45%, 32%, 29%, and 65%, respectively (P < .001). Other factors predictive of SLN status included: patient age (P < .001), tumor size (P < .001), tumor palpability (P < .001), number of SLN removed (P < .001), type of surgery (mastectomy vs. lumpectomy) (P < .001), histologic subtype (P = .048), and the use of immunohistochemistry (P < .001). All of these factors remained significant in the multivariate model except for histologic subtype and biopsy examination type. Conclusions: Biopsy examination type does not independently influence the risk for nodal metastasis.

Original languageEnglish (US)
Pages (from-to)551-556
Number of pages6
JournalAmerican journal of surgery
Volume190
Issue number4
DOIs
StatePublished - Oct 2005

Keywords

  • Biopsy type
  • Breast cancer
  • Sentinel node status

ASJC Scopus subject areas

  • Surgery

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