From July, 1962, to January, 1972, 271 patients with cervical cancer were evaluated, staged, and treated with radiation therapy at the University of Kentucky Medical Center. Six of these patients developed large bowel or bladder fistulas in the absence of recurrent tumor. Radiation-related bowel or bladder injury was found to occur more commonly in patients with pre-existing hypertension or diabetes mellitus. The pathophysiology of vascular disease as an etiologic factor in radiation complications is discussed.
ASJC Scopus subject areas
- Obstetrics and Gynecology