Blood component support in acquired coagulopathic conditions: Is there a method to the madness?

Trailokya Nath Pandit, Ravindra Sarode

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

Acquired coagulopathies are often detected by laboratory investigation in clinical practice. There is a poor correlation between mild to moderate abnormalities of laboratory test and bleeding tendency. Patients who are bleeding due to coagulopathy are often managed with various blood components including plasma, platelets, and cryoprecipitate. However, prophylactic transfusion of these products in a nonbleeding patient to correct mild to moderate abnormality of a coagulation test especially preprocedure is not evidence-based. This article reviews the management of bleeding due to oral anticoagulants and antiplatelet agents, disseminated intravascular coagulation, chronic liver disease, and trauma.

Original languageEnglish (US)
Pages (from-to)S56-S62
JournalAmerican Journal of Hematology
Volume87
Issue numberSUPPL. 1
DOIs
StatePublished - May 2012

ASJC Scopus subject areas

  • Hematology

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