Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication

Gerard Karsenty, Eric N. Olson

Research output: Contribution to journalReview articlepeer-review

183 Scopus citations

Abstract

Most physiological functions originate with the communication between organs. Mouse genetics has revived this holistic view of physiology through the identification of inter-organ communications that are unanticipated, functionally important, and would have been difficult to uncover otherwise. This Review highlights this point by showing how two tissues usually not seen as endocrine ones, bone and striated muscles, influence several physiological processes in a significant manner.

Original languageEnglish (US)
Pages (from-to)1248-1256
Number of pages9
JournalCell
Volume164
Issue number6
DOIs
StatePublished - Mar 10 2016

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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