Boosting with stumps for predicting transcription start sites

Xiaoyue Zhao, Zhenyu Xuan, Michael Q. Zhang

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Promoter prediction is a difficult but important problem in gene finding, and it is critical for elucidating the regulation of gene expression. We introduce a new promoter prediction program, CoreBoost, which applies a boosting technique with stumps to select important small-scale as well as large-scale features. CoreBoost improves greatly on locating transcription start sites. We also demonstrate that by further utilizing some tissue-specific information, better accuracy can be achieved.

Original languageEnglish (US)
Article numberR17
JournalGenome biology
Volume8
Issue number2
DOIs
StatePublished - Feb 2 2007
Externally publishedYes

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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