Bordetella holmesii bacteremia in sickle cell disease

Timothy L. McCavit, Steve Grube, Paula Revell, Charles T. Quinn

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Patients with sickle cell disease (SCD) have an increased risk of invasive bacterial infection because of hyposplenism. Bordetella holmesii is a recently described Gram-negative coccobacillus with an apparent predilection for asplenic hosts. We report two patients with SCD and B. holmesii bacteremia. Fastidious growth in culture and a typically uncomplicated clinical course distinguish B. holmesii infection from other invasive bacterial infections in SCD. Providers for patients with SCD should be aware of this pathogen and ensure that their microbiology laboratories are capable of isolating and identifying this organism.

Original languageEnglish (US)
Pages (from-to)814-816
Number of pages3
JournalPediatric Blood and Cancer
Issue number6
StatePublished - Dec 2008


  • Asplenia
  • Bacteremia
  • Bordetella holmesii
  • Sickle cell disease

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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