Botulinum toxin type A injections to salivary glands: Combination with single event multilevel chemoneurolysis in 2 children with severe spastic quadriplegic cerebral palsy

Heakyung Kim, Yung Lee, Daniel Weiner, Robin Kaye, Anne Marie Cahill, Marc Yudkoff

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

We describe 2 children with severe spastic quadriplegic cerebral palsy (CP) who have significant drooling and frequent aspiration pneumonia. They underwent simultaneous botulinum toxin type A (BTX-A) injections to salivary glands for drooling and prevention of aspiration pneumonia along with single-event multilevel chemoneurolysis (SEMLC) with BTX-A and 5% phenol for severe diffuse spasticity. There was significant improvement in drooling, frequency of aspiration pneumonia, and spasticity without adverse effect. BTX-A injections into the salivary glands, in addition to SEMLC, for these 2 children with medically complicated severe spastic quadriplegic CP, were safe and highly successful procedures, which improved their health-related quality of life.

Original languageEnglish (US)
Pages (from-to)141-144
Number of pages4
JournalArchives of physical medicine and rehabilitation
Volume87
Issue number1
DOIs
StatePublished - Jan 2006
Externally publishedYes

Keywords

  • Botulinum toxin type A
  • Case report
  • Cerebral palsy
  • Pneumonia, aspiration
  • Rehabilitation
  • Salivary glands

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

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